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[Acute and chronic Q fever; epidemiology, symptoms, diagnosis and therapy of infection caused by Coxiella burnetii].
Ned Tijdschr Geneeskd. 2000 Jul 01; 144(27):1303-6.NT

Abstract

Q fever is a zoonosis caused by Coxiella burnetii, an obligate intracellular bacterium. Domestic ungulates and parturient cats are the primary reservoirs of infection. The animals excrete the bacterium in urine, faeces, milk and amniotic fluid. After desiccation the micro-organism spreads via aerosols. After inhalation or ingestion and an incubation period of 2-6 weeks acute Q fever may develop with atypical pneumonia and hepatitis as major clinical symptoms. The infection also may present as a flu-like illness or remain asymptomatic. Generally, the prognosis is favourable. However, endocarditis or another chronic form of Q fever occasionally develops with possibly fatal outcome. Diagnosis relies upon serologic testing with an indirect immunofluorescence method. Doxycycline is the antibiotic of choice in the treatment of Q fever. Endocarditis needs therapy for years with the addition of rifampin or hydroxychloroquine. Q fever is poorly recognised due to the variety of clinical presentations.

Authors+Show Affiliations

Ziekenhuis Eemland, Amersfoort. bartelink@wxs.nlNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comment
English Abstract
Journal Article
Review

Language

dut

PubMed ID

10918908

Citation

Bartelink, A K., et al. "[Acute and Chronic Q Fever; Epidemiology, Symptoms, Diagnosis and Therapy of Infection Caused By Coxiella Burnetii]." Nederlands Tijdschrift Voor Geneeskunde, vol. 144, no. 27, 2000, pp. 1303-6.
Bartelink AK, Stevens H, van Kregten E, et al. [Acute and chronic Q fever; epidemiology, symptoms, diagnosis and therapy of infection caused by Coxiella burnetii]. Ned Tijdschr Geneeskd. 2000;144(27):1303-6.
Bartelink, A. K., Stevens, H., van Kregten, E., Meijer, J. G., Beeres, M. P., & van Deuren, M. (2000). [Acute and chronic Q fever; epidemiology, symptoms, diagnosis and therapy of infection caused by Coxiella burnetii]. Nederlands Tijdschrift Voor Geneeskunde, 144(27), 1303-6.
Bartelink AK, et al. [Acute and Chronic Q Fever; Epidemiology, Symptoms, Diagnosis and Therapy of Infection Caused By Coxiella Burnetii]. Ned Tijdschr Geneeskd. 2000 Jul 1;144(27):1303-6. PubMed PMID: 10918908.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Acute and chronic Q fever; epidemiology, symptoms, diagnosis and therapy of infection caused by Coxiella burnetii]. AU - Bartelink,A K, AU - Stevens,H, AU - van Kregten,E, AU - Meijer,J G, AU - Beeres,M P, AU - van Deuren,M, PY - 2000/8/5/pubmed PY - 2000/9/19/medline PY - 2000/8/5/entrez SP - 1303 EP - 6 JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 144 IS - 27 N2 - Q fever is a zoonosis caused by Coxiella burnetii, an obligate intracellular bacterium. Domestic ungulates and parturient cats are the primary reservoirs of infection. The animals excrete the bacterium in urine, faeces, milk and amniotic fluid. After desiccation the micro-organism spreads via aerosols. After inhalation or ingestion and an incubation period of 2-6 weeks acute Q fever may develop with atypical pneumonia and hepatitis as major clinical symptoms. The infection also may present as a flu-like illness or remain asymptomatic. Generally, the prognosis is favourable. However, endocarditis or another chronic form of Q fever occasionally develops with possibly fatal outcome. Diagnosis relies upon serologic testing with an indirect immunofluorescence method. Doxycycline is the antibiotic of choice in the treatment of Q fever. Endocarditis needs therapy for years with the addition of rifampin or hydroxychloroquine. Q fever is poorly recognised due to the variety of clinical presentations. SN - 0028-2162 UR - https://www.unboundmedicine.com/medline/citation/10918908/[Acute_and_chronic_Q_fever L2 - http://www.diseaseinfosearch.org/result/6127 DB - PRIME DP - Unbound Medicine ER -