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Bispectral index monitoring of sedation during endoscopy.
Gastrointest Endosc. 2000 Aug; 52(2):192-6.GE

Abstract

BACKGROUND

No objective measure of the level of sedation is universally accepted. However, bispectral index monitoring is currently used to objectively measure sedation levels in several clinical settings. This study compares the temporal relationship of bispectral index levels versus the Observer's Assessment of Alertness/Sedation (OAA/S) scale for sedation during endoscopy and proposes a functional bispectral index range for endoscopic procedures.

METHODS

Fifty consecutive adults undergoing endoscopic retrograde cholangiopancreatography, colonoscopy, or esophagogastroduodenoscopy by a single endoscopist were studied. Intravenous sedation was achieved with diazepam and meperidine. Bispectral index levels (0 to 100) and OAA/S scores (1 to 5) were recorded every 3 minutes by a single trained observer.

RESULTS

There were significant temporal correlations between bispectral index levels and OAA/S scores (r = 0.59, p < 0.0001). Bispectral index levels and OAA/S scores corresponded with the need for additional sedation as determined clinically by the endoscopist. An OAA/S score of 3 corresponded to a bispectral index level of 81.49 +/- 9.78.

CONCLUSIONS

Bispectral index monitoring temporally correlates with the OAA/S scale and therefore provides an objective measure of sedation during endoscopy. This preliminary, observational study suggests that a bispectral index level near 82 corresponds with sufficient and functional sedation levels for endoscopy.

Authors+Show Affiliations

Department of Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article

Language

eng

PubMed ID

10922090

Citation

Bower, A L., et al. "Bispectral Index Monitoring of Sedation During Endoscopy." Gastrointestinal Endoscopy, vol. 52, no. 2, 2000, pp. 192-6.
Bower AL, Ripepi A, Dilger J, et al. Bispectral index monitoring of sedation during endoscopy. Gastrointest Endosc. 2000;52(2):192-6.
Bower, A. L., Ripepi, A., Dilger, J., Boparai, N., Brody, F. J., & Ponsky, J. L. (2000). Bispectral index monitoring of sedation during endoscopy. Gastrointestinal Endoscopy, 52(2), 192-6.
Bower AL, et al. Bispectral Index Monitoring of Sedation During Endoscopy. Gastrointest Endosc. 2000;52(2):192-6. PubMed PMID: 10922090.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bispectral index monitoring of sedation during endoscopy. AU - Bower,A L, AU - Ripepi,A, AU - Dilger,J, AU - Boparai,N, AU - Brody,F J, AU - Ponsky,J L, PY - 2000/8/2/pubmed PY - 2000/9/30/medline PY - 2000/8/2/entrez SP - 192 EP - 6 JF - Gastrointestinal endoscopy JO - Gastrointest Endosc VL - 52 IS - 2 N2 - BACKGROUND: No objective measure of the level of sedation is universally accepted. However, bispectral index monitoring is currently used to objectively measure sedation levels in several clinical settings. This study compares the temporal relationship of bispectral index levels versus the Observer's Assessment of Alertness/Sedation (OAA/S) scale for sedation during endoscopy and proposes a functional bispectral index range for endoscopic procedures. METHODS: Fifty consecutive adults undergoing endoscopic retrograde cholangiopancreatography, colonoscopy, or esophagogastroduodenoscopy by a single endoscopist were studied. Intravenous sedation was achieved with diazepam and meperidine. Bispectral index levels (0 to 100) and OAA/S scores (1 to 5) were recorded every 3 minutes by a single trained observer. RESULTS: There were significant temporal correlations between bispectral index levels and OAA/S scores (r = 0.59, p < 0.0001). Bispectral index levels and OAA/S scores corresponded with the need for additional sedation as determined clinically by the endoscopist. An OAA/S score of 3 corresponded to a bispectral index level of 81.49 +/- 9.78. CONCLUSIONS: Bispectral index monitoring temporally correlates with the OAA/S scale and therefore provides an objective measure of sedation during endoscopy. This preliminary, observational study suggests that a bispectral index level near 82 corresponds with sufficient and functional sedation levels for endoscopy. SN - 0016-5107 UR - https://www.unboundmedicine.com/medline/citation/10922090/Bispectral_index_monitoring_of_sedation_during_endoscopy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0016-5107(00)99099-0 DB - PRIME DP - Unbound Medicine ER -