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[Detecting cytokines in patients with preterm premature rupture of membrane].
Zhonghua Yi Xue Za Zhi. 1998 Mar; 78(3):216-7.ZY

Abstract

OBJECTIVE

To study the relationship of maternal blood and amniotic fluid cytokine levels in patients with preterm premature rupture of membrane and chorioamnionitis.

METHODS

IL8 and TNF alpha levels of maternal blood and amniotic fluid were determined by 125I radioimmunoassay (RIA) and an enzyme-labeled immunosorbent assay (ELISA). Chorioamnionitis was diagnosed by fetal membrane histology.

RESULTS

The maternal serum IL8 levels and amniotic fluid IL8, TNF alpha levels were higher than those of controls (P < 0.05). There was significant relationship between maternal serum and amniotic fluid IL8, TNF alpha with the time of the premature rupture of membanes. The longer the time the higher the maternal serum IL8 and amniotic fluid IL8, TNF alpha; There were 13 patients with chorioamnionitis, and their maternal serum and amniotic fluid IL8, TNF alpha were higher than those of patients with non-chorioamnionitis (P < 0.01-0.05).

CONCLUSION

IL8, TNF alpha levels of maternal serum and amniotic fluid are valuable clinical indexes in identification of chorioamnionitis in patients with preterm premature rupture of membranes.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, 208th Hospital of PLA, Changchun.No affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

10923535

Citation

Wang, L, and W Zhang. "[Detecting Cytokines in Patients With Preterm Premature Rupture of Membrane]." Zhonghua Yi Xue Za Zhi, vol. 78, no. 3, 1998, pp. 216-7.
Wang L, Zhang W. [Detecting cytokines in patients with preterm premature rupture of membrane]. Zhonghua Yi Xue Za Zhi. 1998;78(3):216-7.
Wang, L., & Zhang, W. (1998). [Detecting cytokines in patients with preterm premature rupture of membrane]. Zhonghua Yi Xue Za Zhi, 78(3), 216-7.
Wang L, Zhang W. [Detecting Cytokines in Patients With Preterm Premature Rupture of Membrane]. Zhonghua Yi Xue Za Zhi. 1998;78(3):216-7. PubMed PMID: 10923535.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Detecting cytokines in patients with preterm premature rupture of membrane]. AU - Wang,L, AU - Zhang,W, PY - 2000/8/3/pubmed PY - 2000/9/23/medline PY - 2000/8/3/entrez SP - 216 EP - 7 JF - Zhonghua yi xue za zhi JO - Zhonghua Yi Xue Za Zhi VL - 78 IS - 3 N2 - OBJECTIVE: To study the relationship of maternal blood and amniotic fluid cytokine levels in patients with preterm premature rupture of membrane and chorioamnionitis. METHODS: IL8 and TNF alpha levels of maternal blood and amniotic fluid were determined by 125I radioimmunoassay (RIA) and an enzyme-labeled immunosorbent assay (ELISA). Chorioamnionitis was diagnosed by fetal membrane histology. RESULTS: The maternal serum IL8 levels and amniotic fluid IL8, TNF alpha levels were higher than those of controls (P < 0.05). There was significant relationship between maternal serum and amniotic fluid IL8, TNF alpha with the time of the premature rupture of membanes. The longer the time the higher the maternal serum IL8 and amniotic fluid IL8, TNF alpha; There were 13 patients with chorioamnionitis, and their maternal serum and amniotic fluid IL8, TNF alpha were higher than those of patients with non-chorioamnionitis (P < 0.01-0.05). CONCLUSION: IL8, TNF alpha levels of maternal serum and amniotic fluid are valuable clinical indexes in identification of chorioamnionitis in patients with preterm premature rupture of membranes. SN - 0376-2491 UR - https://www.unboundmedicine.com/medline/citation/10923535/[Detecting_cytokines_in_patients_with_preterm_premature_rupture_of_membrane]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0376-2491&amp;year=1998&amp;vol=78&amp;issue=3&amp;fpage=216 DB - PRIME DP - Unbound Medicine ER -