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Gluten-dependent diabetes-related and thyroid-related autoantibodies in patients with celiac disease.
Patients with celiac disease are at high risk of having autoimmune disorders. Moreover, untreated patients with celiac disease have been found to have a higher than expected prevalence of organ-specific autoantibodies. In a prospective study of 90 patients with celiac disease, we found that the prevalence of diabetes and thyroid-related serum antibodies was 11.1% and 14.4%, respectively. Like antiendomysium autoantibodies, these organ-specific antibodies seem to be gluten-dependent and tend to disappear during a gluten-free diet.
Clinica Pediatrica e Laboratorio di Analisi, IRCCS "Burlo Garofolo" Trieste, Trieste, Italy., , , ,
Diabetes Mellitus, Type 1
Pub Type(s)Journal Article