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[Histoplasmosis: not only a tropical disease].
Recenti Prog Med. 2000 Jul-Aug; 91(7-8):396-401.RP

Abstract

Histoplasmosis is a fungal infection resulting from inhalation of spores from the fungus Histoplasma capsulatum; it is known to be endemic in various parts of the world, especially in North and Latin America, and can produce a spectrum of illness, from subclinical infection to progressive disseminated disease. The majority of infected persons have an asymptomatic, self-limiting illness. Clinical pneumonia occurs in those with exposure to a large number of infecting spores. Disseminated histoplasmosis usually occurs in immunosuppressed patients or in patients with chronic illness. Diagnosis is best made by visualization of yeast in tissue or by culture. In most cases, amphotericin B is the initial drug of choice, followed by one of the azoles for lifelong maintenance therapy. Itraconazole is the drug of choice for treatment of disseminated histoplasmosis in less severe cases, while fluconazole therapy for histoplasmosis is only moderately effective.

Authors+Show Affiliations

Divisione di Medicina d'Urgenza, Ospedale Maggiore, IRCCS, Policlinico, Milano. rino_bregani@yahoo.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

ita

PubMed ID

10932927

Citation

Bregani, E R., et al. "[Histoplasmosis: Not Only a Tropical Disease]." Recenti Progressi in Medicina, vol. 91, no. 7-8, 2000, pp. 396-401.
Bregani ER, Van Tien T, Ceraldi T, et al. [Histoplasmosis: not only a tropical disease]. Recenti Prog Med. 2000;91(7-8):396-401.
Bregani, E. R., Van Tien, T., Ceraldi, T., Delfitto, C., & Figini, G. (2000). [Histoplasmosis: not only a tropical disease]. Recenti Progressi in Medicina, 91(7-8), 396-401.
Bregani ER, et al. [Histoplasmosis: Not Only a Tropical Disease]. Recenti Prog Med. 2000 Jul-Aug;91(7-8):396-401. PubMed PMID: 10932927.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Histoplasmosis: not only a tropical disease]. AU - Bregani,E R, AU - Van Tien,T, AU - Ceraldi,T, AU - Delfitto,C, AU - Figini,G, PY - 2000/8/10/pubmed PY - 2000/9/23/medline PY - 2000/8/10/entrez SP - 396 EP - 401 JF - Recenti progressi in medicina JO - Recenti Prog Med VL - 91 IS - 7-8 N2 - Histoplasmosis is a fungal infection resulting from inhalation of spores from the fungus Histoplasma capsulatum; it is known to be endemic in various parts of the world, especially in North and Latin America, and can produce a spectrum of illness, from subclinical infection to progressive disseminated disease. The majority of infected persons have an asymptomatic, self-limiting illness. Clinical pneumonia occurs in those with exposure to a large number of infecting spores. Disseminated histoplasmosis usually occurs in immunosuppressed patients or in patients with chronic illness. Diagnosis is best made by visualization of yeast in tissue or by culture. In most cases, amphotericin B is the initial drug of choice, followed by one of the azoles for lifelong maintenance therapy. Itraconazole is the drug of choice for treatment of disseminated histoplasmosis in less severe cases, while fluconazole therapy for histoplasmosis is only moderately effective. SN - 0034-1193 UR - https://www.unboundmedicine.com/medline/citation/10932927/[Histoplasmosis:_not_only_a_tropical_disease]_ L2 - https://medlineplus.gov/histoplasmosis.html DB - PRIME DP - Unbound Medicine ER -