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Bone mineral density in older non-Hispanic Caucasian and Mexican-American women: relationship to lean and fat mass.
Ann Hum Biol 2000 Jul-Aug; 27(4):331-44AH

Abstract

PRIMARY OBJECTIVE

The prevalence of osteoporotic fracture is higher in non-Hispanic Caucasian (NHC) than Mexican-American (MA) women in the USA. The present study examined bone mineral density (BMD) in these two ethnic groups and the association between BMD and body composition.

RESEARCH DESIGN

Cross-sectional.

SUBJECTS

Sixty-two NHC and 54 MA women, aged 60-86 years, with a body mass index (kgm(-2)) of <30.

METHODS

BMD (gcm(-2)) of the spine (L2-4), hip (femoral neck, trochanter, Ward's triangle) and whole body was determined by dual-energy X-ray absorptiometry (DXA). Bone mineral-free lean mass (LM) and fat mass (FM) and several ratios of body fat distribution were also assessed by DXA.

RESULTS

There was no difference in age (NHC, 69.5+/-0.7; MA 69.5+/-0.9 years; mean +/- SEM) or body mass, but MA women were shorter with a higher truncal adiposity (p < 0.001). There was no significant difference in BMD between groups, however, adjusting for height resulted in higher hip and whole body BMD in MA women (p < 0.01). When volumetric bone density was calculated (bone mineral apparent density; BMAD, gcm(-3)), a trend for higher values in MA women was observed at the femoral neck (p = 0.018). LM contributed independently to BMD at the spine and hip in NHC women, with FM also contributing at the femoral neck. In MA women, LM was an independent contributor to lumbar spine and trochanter BMD, and both LM and FM contributed to whole body BMD. However, the effects of LM and FM were removed in both groups when BMD was adjusted for body or bone size, the only exception being at the trochanter in NHC women.

CONCLUSIONS

These results indicate that MA women have higher bone density at the proximal femur than NHC women, which may partially account for their lower rate of hip fracture. Further, differences in bone density between the two ethnic groups do not appear to be dependent on soft-tissue composition.

Authors+Show Affiliations

The Aging Study Unit, Palo Alto, California, USA. taaffed@exmur.nia.nih.govNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

10942342

Citation

Taaffe, D R., et al. "Bone Mineral Density in Older non-Hispanic Caucasian and Mexican-American Women: Relationship to Lean and Fat Mass." Annals of Human Biology, vol. 27, no. 4, 2000, pp. 331-44.
Taaffe DR, Villa ML, Holloway L, et al. Bone mineral density in older non-Hispanic Caucasian and Mexican-American women: relationship to lean and fat mass. Ann Hum Biol. 2000;27(4):331-44.
Taaffe, D. R., Villa, M. L., Holloway, L., & Marcus, R. (2000). Bone mineral density in older non-Hispanic Caucasian and Mexican-American women: relationship to lean and fat mass. Annals of Human Biology, 27(4), pp. 331-44.
Taaffe DR, et al. Bone Mineral Density in Older non-Hispanic Caucasian and Mexican-American Women: Relationship to Lean and Fat Mass. Ann Hum Biol. 2000;27(4):331-44. PubMed PMID: 10942342.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bone mineral density in older non-Hispanic Caucasian and Mexican-American women: relationship to lean and fat mass. AU - Taaffe,D R, AU - Villa,M L, AU - Holloway,L, AU - Marcus,R, PY - 2000/8/15/pubmed PY - 2001/2/28/medline PY - 2000/8/15/entrez SP - 331 EP - 44 JF - Annals of human biology JO - Ann. Hum. Biol. VL - 27 IS - 4 N2 - PRIMARY OBJECTIVE: The prevalence of osteoporotic fracture is higher in non-Hispanic Caucasian (NHC) than Mexican-American (MA) women in the USA. The present study examined bone mineral density (BMD) in these two ethnic groups and the association between BMD and body composition. RESEARCH DESIGN: Cross-sectional. SUBJECTS: Sixty-two NHC and 54 MA women, aged 60-86 years, with a body mass index (kgm(-2)) of <30. METHODS: BMD (gcm(-2)) of the spine (L2-4), hip (femoral neck, trochanter, Ward's triangle) and whole body was determined by dual-energy X-ray absorptiometry (DXA). Bone mineral-free lean mass (LM) and fat mass (FM) and several ratios of body fat distribution were also assessed by DXA. RESULTS: There was no difference in age (NHC, 69.5+/-0.7; MA 69.5+/-0.9 years; mean +/- SEM) or body mass, but MA women were shorter with a higher truncal adiposity (p < 0.001). There was no significant difference in BMD between groups, however, adjusting for height resulted in higher hip and whole body BMD in MA women (p < 0.01). When volumetric bone density was calculated (bone mineral apparent density; BMAD, gcm(-3)), a trend for higher values in MA women was observed at the femoral neck (p = 0.018). LM contributed independently to BMD at the spine and hip in NHC women, with FM also contributing at the femoral neck. In MA women, LM was an independent contributor to lumbar spine and trochanter BMD, and both LM and FM contributed to whole body BMD. However, the effects of LM and FM were removed in both groups when BMD was adjusted for body or bone size, the only exception being at the trochanter in NHC women. CONCLUSIONS: These results indicate that MA women have higher bone density at the proximal femur than NHC women, which may partially account for their lower rate of hip fracture. Further, differences in bone density between the two ethnic groups do not appear to be dependent on soft-tissue composition. SN - 0301-4460 UR - https://www.unboundmedicine.com/medline/citation/10942342/Bone_mineral_density_in_older_non_Hispanic_Caucasian_and_Mexican_American_women:_relationship_to_lean_and_fat_mass_ L2 - https://medlineplus.gov/bonedensity.html DB - PRIME DP - Unbound Medicine ER -