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High-altitude cerebral edema (HACE): the Denver/Front Range experience.
Semin Neurol. 2000; 20(2):209-17.SN

Abstract

High-altitude cerebral edema (HACE) is a potentially fatal metabolic encephalopathy associated with a time-dependent exposure to the hypobaric hypoxia of altitude. Symptoms commonly are headache, ataxia, and confusion progressing to stupor and coma. HACE is often preceded by symptoms of acute mountain sickness and coupled, in its severe form, with high-altitude pulmonary edema. Although HACE is mostly seen at altitudes above that of the Denver/Front Range visitor-skier locations, we report our observations over a 13-year period of skier-visitor HACE patients. It is believed that this is a form of vasogenic edema, and it is responsive to expeditious treatment with a successful outcome.

Authors+Show Affiliations

Department of Neurology, University of Colorado School of Medicine, St. Anthony's Hospital Denver, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

10946741

Citation

Yarnell, P R., et al. "High-altitude Cerebral Edema (HACE): the Denver/Front Range Experience." Seminars in Neurology, vol. 20, no. 2, 2000, pp. 209-17.
Yarnell PR, Heit J, Hackett PH. High-altitude cerebral edema (HACE): the Denver/Front Range experience. Semin Neurol. 2000;20(2):209-17.
Yarnell, P. R., Heit, J., & Hackett, P. H. (2000). High-altitude cerebral edema (HACE): the Denver/Front Range experience. Seminars in Neurology, 20(2), 209-17.
Yarnell PR, Heit J, Hackett PH. High-altitude Cerebral Edema (HACE): the Denver/Front Range Experience. Semin Neurol. 2000;20(2):209-17. PubMed PMID: 10946741.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - High-altitude cerebral edema (HACE): the Denver/Front Range experience. AU - Yarnell,P R, AU - Heit,J, AU - Hackett,P H, PY - 2000/8/18/pubmed PY - 2001/2/28/medline PY - 2000/8/18/entrez SP - 209 EP - 17 JF - Seminars in neurology JO - Semin Neurol VL - 20 IS - 2 N2 - High-altitude cerebral edema (HACE) is a potentially fatal metabolic encephalopathy associated with a time-dependent exposure to the hypobaric hypoxia of altitude. Symptoms commonly are headache, ataxia, and confusion progressing to stupor and coma. HACE is often preceded by symptoms of acute mountain sickness and coupled, in its severe form, with high-altitude pulmonary edema. Although HACE is mostly seen at altitudes above that of the Denver/Front Range visitor-skier locations, we report our observations over a 13-year period of skier-visitor HACE patients. It is believed that this is a form of vasogenic edema, and it is responsive to expeditious treatment with a successful outcome. SN - 0271-8235 UR - https://www.unboundmedicine.com/medline/citation/10946741/High_altitude_cerebral_edema__HACE_:_the_Denver/Front_Range_experience_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-9830 DB - PRIME DP - Unbound Medicine ER -