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[Clinical and prognostic characteristics associated with addictive comorbidity in hospitalized psychiatric patients].
Encephale 2000 May-Jun; 26(3):16-23E

Abstract

The aims of this study were to estimate: 1) the prevalence of substance use disorder, 2) the social and clinical characteristics associated to such a comorbid disorder in patients hospitalised in psychiatry.

METHOD

Patients consecutively hospitalised for a non-addictive disorder were included in the present survey. A standardised method was used to collect information on clinical and social characteristics. DSM IV diagnoses, including those of substance use, were made using a structured diagnostic interview and all available clinical and historical informations collected during the hospital stay.

RESULTS

We have included 127 patients fulfilling the diagnostic criteria for affective disorders (n = 61), non-affective psychotic disorder (schizophrenia, schizoaffective disorder, delusional disorder, other psychotic disorders, n = 50) and personality disorder (n = 16). Among these patients, 11.8% presented with a current abuse/dependence to alcohol (lifetime prevalence: 25.2%), 11% to cannabis (lifetime prevalence: 22.8%). The lifetime prevalence for any other substance disorder was 2.4%. The subjects presenting with an abuse/dependence to alcohol had a higher rate of psychiatric hospitalisation (OR = 2.9; 95% CI 1.0-8.1; p = 0.04) and had more frequently a history of attempted suicide (OR = 2.6; 95% CI 1.0-6.5; p = 0.04). The cannabis misuse was associated with medication noncompliance (OR = 3.1; 95% CI 1.1-9.1; p = 0.04) and more frequent penal problems (OR = 15.0; 95% CI 2.9-78.7; p = 0.001).

CONCLUSION

Cannabis and alcohol misuse have a negative, but different, impact on social adaptation and clinical outcome in subjects with psychiatric disorder. These results confirm the necessity to systematically assess this type of comorbid disorder and to distinguish the different substances.

Authors+Show Affiliations

Université Victor-Segalen Bordeaux 2, CH Charles-Perrens, Centre Carreire, Bordeaux.No affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

fre

PubMed ID

10951902

Citation

Liraud, F, and H Verdoux. "[Clinical and Prognostic Characteristics Associated With Addictive Comorbidity in Hospitalized Psychiatric Patients]." L'Encephale, vol. 26, no. 3, 2000, pp. 16-23.
Liraud F, Verdoux H. [Clinical and prognostic characteristics associated with addictive comorbidity in hospitalized psychiatric patients]. Encephale. 2000;26(3):16-23.
Liraud, F., & Verdoux, H. (2000). [Clinical and prognostic characteristics associated with addictive comorbidity in hospitalized psychiatric patients]. L'Encephale, 26(3), pp. 16-23.
Liraud F, Verdoux H. [Clinical and Prognostic Characteristics Associated With Addictive Comorbidity in Hospitalized Psychiatric Patients]. Encephale. 2000;26(3):16-23. PubMed PMID: 10951902.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical and prognostic characteristics associated with addictive comorbidity in hospitalized psychiatric patients]. AU - Liraud,F, AU - Verdoux,H, PY - 2000/8/22/pubmed PY - 2000/10/21/medline PY - 2000/8/22/entrez SP - 16 EP - 23 JF - L'Encephale JO - Encephale VL - 26 IS - 3 N2 - UNLABELLED: The aims of this study were to estimate: 1) the prevalence of substance use disorder, 2) the social and clinical characteristics associated to such a comorbid disorder in patients hospitalised in psychiatry. METHOD: Patients consecutively hospitalised for a non-addictive disorder were included in the present survey. A standardised method was used to collect information on clinical and social characteristics. DSM IV diagnoses, including those of substance use, were made using a structured diagnostic interview and all available clinical and historical informations collected during the hospital stay. RESULTS: We have included 127 patients fulfilling the diagnostic criteria for affective disorders (n = 61), non-affective psychotic disorder (schizophrenia, schizoaffective disorder, delusional disorder, other psychotic disorders, n = 50) and personality disorder (n = 16). Among these patients, 11.8% presented with a current abuse/dependence to alcohol (lifetime prevalence: 25.2%), 11% to cannabis (lifetime prevalence: 22.8%). The lifetime prevalence for any other substance disorder was 2.4%. The subjects presenting with an abuse/dependence to alcohol had a higher rate of psychiatric hospitalisation (OR = 2.9; 95% CI 1.0-8.1; p = 0.04) and had more frequently a history of attempted suicide (OR = 2.6; 95% CI 1.0-6.5; p = 0.04). The cannabis misuse was associated with medication noncompliance (OR = 3.1; 95% CI 1.1-9.1; p = 0.04) and more frequent penal problems (OR = 15.0; 95% CI 2.9-78.7; p = 0.001). CONCLUSION: Cannabis and alcohol misuse have a negative, but different, impact on social adaptation and clinical outcome in subjects with psychiatric disorder. These results confirm the necessity to systematically assess this type of comorbid disorder and to distinguish the different substances. SN - 0013-7006 UR - https://www.unboundmedicine.com/medline/citation/10951902/[Clinical_and_prognostic_characteristics_associated_with_addictive_comorbidity_in_hospitalized_psychiatric_patients]_ L2 - https://medlineplus.gov/childmentalhealth.html DB - PRIME DP - Unbound Medicine ER -