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[Results of stereotactic breast biopsy in mammographically suspicious lesions].
Rofo. 2000 Apr; 172(4):346-53.ROFO

Abstract

PURPOSE

The object of this study was to evaluate the diagnostic accuracy of the stereotactic large core breast biopsy in the histological assessment of mammographically suspicious lesions.

MATERIAL AND METHODS

In 106 patients with a mammographically suspicious lesion, 67 with a mass (55 non-palpable, 12 palpable and 39 with microcalcification stereotactic large core biopsies were performed. Samples were obtained in the prone position under local anesthesia with a 14-gauge needle and an automated high-speed gun. An average of 4.3 cores per lesion were acquired. In 68 patients (64%) an additional surgical biopsy was performed, 38 (36%) had clinical and mammographic follow-up.

RESULTS

In 4 of the 106 stereotactic biopsies insufficient material for the histological examination was obtained. In the 68 core biopsies with surgical correlation there were no false-positive, but 2 false-negative results with regard to the malignancy of the lesion (sensitivity: 93.8%; specificity: 100%). The 2 false-negative results were obtained in lesions that were mammographically judged as malignant while histology of the stereotactic biopsy showed fibrosis. The stereotactic large core breast biopsy was well tolerated by all patients. No clinically significant complications occurred.

CONCLUSION

The stereotactic large core breast biopsy of a mammographically suspicious lesion can be performed with a high diagnostic accuracy. A correlation of the mammographic and histological findings and a follow-up program are necessary in order to recognize false-negative results early and to avoid a delay in the diagnosis.

Authors+Show Affiliations

Radiologische Klinik, Städtische Kliniken Dortmund, Lehrstuhl für Radiologie und MikroTherapie, Universität Witten/Herdecke. HORSTJAEGER@T-ONLINE.DENo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

ger

PubMed ID

10961219

Citation

Jäger, H J., et al. "[Results of Stereotactic Breast Biopsy in Mammographically Suspicious Lesions]." RoFo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin, vol. 172, no. 4, 2000, pp. 346-53.
Jäger HJ, Schatz TH, Mehring UM, et al. [Results of stereotactic breast biopsy in mammographically suspicious lesions]. Rofo. 2000;172(4):346-53.
Jäger, H. J., Schatz, T. H., Mehring, U. M., Kubasch, M., Hennigs, S., Gissler, H. M., Spörl, H. D., & Mathias, K. D. (2000). [Results of stereotactic breast biopsy in mammographically suspicious lesions]. RoFo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin, 172(4), 346-53.
Jäger HJ, et al. [Results of Stereotactic Breast Biopsy in Mammographically Suspicious Lesions]. Rofo. 2000;172(4):346-53. PubMed PMID: 10961219.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Results of stereotactic breast biopsy in mammographically suspicious lesions]. AU - Jäger,H J, AU - Schatz,T H, AU - Mehring,U M, AU - Kubasch,M, AU - Hennigs,S, AU - Gissler,H M, AU - Spörl,H D, AU - Mathias,K D, PY - 2000/8/29/pubmed PY - 2000/9/9/medline PY - 2000/8/29/entrez SP - 346 EP - 53 JF - RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin JO - Rofo VL - 172 IS - 4 N2 - PURPOSE: The object of this study was to evaluate the diagnostic accuracy of the stereotactic large core breast biopsy in the histological assessment of mammographically suspicious lesions. MATERIAL AND METHODS: In 106 patients with a mammographically suspicious lesion, 67 with a mass (55 non-palpable, 12 palpable and 39 with microcalcification stereotactic large core biopsies were performed. Samples were obtained in the prone position under local anesthesia with a 14-gauge needle and an automated high-speed gun. An average of 4.3 cores per lesion were acquired. In 68 patients (64%) an additional surgical biopsy was performed, 38 (36%) had clinical and mammographic follow-up. RESULTS: In 4 of the 106 stereotactic biopsies insufficient material for the histological examination was obtained. In the 68 core biopsies with surgical correlation there were no false-positive, but 2 false-negative results with regard to the malignancy of the lesion (sensitivity: 93.8%; specificity: 100%). The 2 false-negative results were obtained in lesions that were mammographically judged as malignant while histology of the stereotactic biopsy showed fibrosis. The stereotactic large core breast biopsy was well tolerated by all patients. No clinically significant complications occurred. CONCLUSION: The stereotactic large core breast biopsy of a mammographically suspicious lesion can be performed with a high diagnostic accuracy. A correlation of the mammographic and histological findings and a follow-up program are necessary in order to recognize false-negative results early and to avoid a delay in the diagnosis. SN - 1438-9029 UR - https://www.unboundmedicine.com/medline/citation/10961219/[Results_of_stereotactic_breast_biopsy_in_mammographically_suspicious_lesions]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-348 DB - PRIME DP - Unbound Medicine ER -