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Premorbid functioning in a national population of male twins discordant for psychoses.
Am J Psychiatry. 2000 Sep; 157(9):1514-6.AJ

Abstract

OBJECTIVE

The goal of the current study was to compare premorbid behavioral and cognitive functioning between co-twins discordant for psychotic disorder and between these pairs of twins and pairs of twins with no psychotic disorders.

METHOD

The authors linked data from the Israeli Draft Board Registry, which contains cognitive and behavioral assessments of all 16-17-year-old male Israeli twins, with data from the National Psychiatric Hospitalization Case Registry. Pairs of male twins who were healthy at the time of testing but discordant for psychoses later on were compared with one another and with pairs of healthy male twins.

RESULTS

The affected twins performed significantly worse than healthy twins on measures of individual autonomy, social functioning, and physical activity and nonsignificantly worse on measures of abstract reasoning. There were no significant differences in cognitive or behavioral scores between the co-twins who did or did not develop psychotic disorders.

CONCLUSIONS

The authors conclude that these findings underscore the familial nature of behavioral and cognitive deficits antecedent to psychoses.

Authors+Show Affiliations

Chaim Sheba Medical Center, Bar Ilan University, Ramat Gan, Israel.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Twin Study

Language

eng

PubMed ID

10964874

Citation

Reichenberg, A, et al. "Premorbid Functioning in a National Population of Male Twins Discordant for Psychoses." The American Journal of Psychiatry, vol. 157, no. 9, 2000, pp. 1514-6.
Reichenberg A, Rabinowitz J, Weiser M, et al. Premorbid functioning in a national population of male twins discordant for psychoses. Am J Psychiatry. 2000;157(9):1514-6.
Reichenberg, A., Rabinowitz, J., Weiser, M., Mark, M., Kaplan, Z., & Davidson, M. (2000). Premorbid functioning in a national population of male twins discordant for psychoses. The American Journal of Psychiatry, 157(9), 1514-6.
Reichenberg A, et al. Premorbid Functioning in a National Population of Male Twins Discordant for Psychoses. Am J Psychiatry. 2000;157(9):1514-6. PubMed PMID: 10964874.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Premorbid functioning in a national population of male twins discordant for psychoses. AU - Reichenberg,A, AU - Rabinowitz,J, AU - Weiser,M, AU - Mark,M, AU - Kaplan,Z, AU - Davidson,M, PY - 2000/8/31/pubmed PY - 2000/9/23/medline PY - 2000/8/31/entrez SP - 1514 EP - 6 JF - The American journal of psychiatry JO - Am J Psychiatry VL - 157 IS - 9 N2 - OBJECTIVE: The goal of the current study was to compare premorbid behavioral and cognitive functioning between co-twins discordant for psychotic disorder and between these pairs of twins and pairs of twins with no psychotic disorders. METHOD: The authors linked data from the Israeli Draft Board Registry, which contains cognitive and behavioral assessments of all 16-17-year-old male Israeli twins, with data from the National Psychiatric Hospitalization Case Registry. Pairs of male twins who were healthy at the time of testing but discordant for psychoses later on were compared with one another and with pairs of healthy male twins. RESULTS: The affected twins performed significantly worse than healthy twins on measures of individual autonomy, social functioning, and physical activity and nonsignificantly worse on measures of abstract reasoning. There were no significant differences in cognitive or behavioral scores between the co-twins who did or did not develop psychotic disorders. CONCLUSIONS: The authors conclude that these findings underscore the familial nature of behavioral and cognitive deficits antecedent to psychoses. SN - 0002-953X UR - https://www.unboundmedicine.com/medline/citation/10964874/Premorbid_functioning_in_a_national_population_of_male_twins_discordant_for_psychoses_ L2 - https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.157.9.1514?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -