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Birth defects prevalence among infants of Persian Gulf War veterans born in Hawaii, 1989-1993.
Teratology. 2000 Oct; 62(4):195-204.T

Abstract

BACKGROUND

Gulf War veterans (GWVs) have expressed concern about possible teratogenic exposures. However, epidemiologic studies on birth defects prevalence among their progeny have been limited to military hospitals, anomalies diagnosed among newborns, or self-reported data. To measure the prevalence of selected birth defects among infants of GWVs and nondeployed veterans (NDVs) in Hawaii, using birth defects surveillance records.

METHODS

Personal identifiers of 684,645 GWVs and 1,587,102 NDVs and their families were matched against birth certificate records of 99,545 live births reported to the State of Hawaii Department of Health between 1989 and 1993 to identify births to military personnel. These births were matched with records from the Hawaii Birth Defects Program.

RESULTS

A total of 17,182 military infants (3,717 GWV infants and 13,465 NDV infants) were identified. Of these, 367 infants (2.14/100 live births) were identified with one or more of 48 major birth defects diagnoses. The prevalence of the 48 birth defects were similar for GWV and NDV infants during the prewar and postwar periods, and among GWV infants who were conceived before and after the Gulf war.

CONCLUSIONS

The results must be interpreted with caution because of the small number of affected infants in each birth defects category. This study demonstrated the feasibility of measuring birth defects prevalence among military infants through multiple data linkage. Further, it included live births to parents who had separated from the military, births in civilian hospitals, and birth defects diagnosed through the first year of life.

Authors+Show Affiliations

DoD Center for Deployment Health Research, Naval Health Research Center, San Diego, California 92186, USA. araneta@nhrc.navy.milNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

10992261

Citation

Araneta, M R., et al. "Birth Defects Prevalence Among Infants of Persian Gulf War Veterans Born in Hawaii, 1989-1993." Teratology, vol. 62, no. 4, 2000, pp. 195-204.
Araneta MR, Destiche DA, Schlangen KM, et al. Birth defects prevalence among infants of Persian Gulf War veterans born in Hawaii, 1989-1993. Teratology. 2000;62(4):195-204.
Araneta, M. R., Destiche, D. A., Schlangen, K. M., Merz, R. D., Forrester, M. B., & Gray, G. C. (2000). Birth defects prevalence among infants of Persian Gulf War veterans born in Hawaii, 1989-1993. Teratology, 62(4), 195-204.
Araneta MR, et al. Birth Defects Prevalence Among Infants of Persian Gulf War Veterans Born in Hawaii, 1989-1993. Teratology. 2000;62(4):195-204. PubMed PMID: 10992261.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Birth defects prevalence among infants of Persian Gulf War veterans born in Hawaii, 1989-1993. AU - Araneta,M R, AU - Destiche,D A, AU - Schlangen,K M, AU - Merz,R D, AU - Forrester,M B, AU - Gray,G C, PY - 2000/9/19/pubmed PY - 2001/2/28/medline PY - 2000/9/19/entrez SP - 195 EP - 204 JF - Teratology JO - Teratology VL - 62 IS - 4 N2 - BACKGROUND: Gulf War veterans (GWVs) have expressed concern about possible teratogenic exposures. However, epidemiologic studies on birth defects prevalence among their progeny have been limited to military hospitals, anomalies diagnosed among newborns, or self-reported data. To measure the prevalence of selected birth defects among infants of GWVs and nondeployed veterans (NDVs) in Hawaii, using birth defects surveillance records. METHODS: Personal identifiers of 684,645 GWVs and 1,587,102 NDVs and their families were matched against birth certificate records of 99,545 live births reported to the State of Hawaii Department of Health between 1989 and 1993 to identify births to military personnel. These births were matched with records from the Hawaii Birth Defects Program. RESULTS: A total of 17,182 military infants (3,717 GWV infants and 13,465 NDV infants) were identified. Of these, 367 infants (2.14/100 live births) were identified with one or more of 48 major birth defects diagnoses. The prevalence of the 48 birth defects were similar for GWV and NDV infants during the prewar and postwar periods, and among GWV infants who were conceived before and after the Gulf war. CONCLUSIONS: The results must be interpreted with caution because of the small number of affected infants in each birth defects category. This study demonstrated the feasibility of measuring birth defects prevalence among military infants through multiple data linkage. Further, it included live births to parents who had separated from the military, births in civilian hospitals, and birth defects diagnosed through the first year of life. SN - 0040-3709 UR - https://www.unboundmedicine.com/medline/citation/10992261/Birth_defects_prevalence_among_infants_of_Persian_Gulf_War_veterans_born_in_Hawaii_1989_1993_ L2 - https://doi.org/10.1002/1096-9926(200010)62:4<195::AID-TERA5>3.0.CO;2-5 DB - PRIME DP - Unbound Medicine ER -