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Rapidly progressing mycosis fungoides presenting as follicular mucinosis.
J Am Acad Dermatol. 2000 Oct; 43(4):635-40.JA

Abstract

Follicular mucinosis can occur as a primary idiopathic disorder or can arise in association with benign or malignant disease, most notably mycosis fungoides. We describe a patient with an aggressive folliculotropic variant of mycosis fungoides that initially presented as follicular mucinosis with alopecia. One month after the diagnosis of follicular mucinosis, a diagnosis of mycosis fungoides was made, and 3 months later inguinal lymph node involvement with mycosis fungoides developed. A skin biopsy specimen demonstrated prominent follicular mucinosis with folliculotropism of atypical cells and intrafollicular Pautrier's microabscesses. As demonstrated in this case, follicular mucinosis can be a presenting sign of rapidly progressive mycosis fungoides. In our review of follicular mucinosis and its association with mycosis fungoides, we found that the folliculotropic variant of mycosis fungoides appears more commonly to have an aggressive course than classic mycosis fungoides.

Authors+Show Affiliations

Dermatopathology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11004619

Citation

Bonta, M D., et al. "Rapidly Progressing Mycosis Fungoides Presenting as Follicular Mucinosis." Journal of the American Academy of Dermatology, vol. 43, no. 4, 2000, pp. 635-40.
Bonta MD, Tannous ZS, Demierre MF, et al. Rapidly progressing mycosis fungoides presenting as follicular mucinosis. J Am Acad Dermatol. 2000;43(4):635-40.
Bonta, M. D., Tannous, Z. S., Demierre, M. F., Gonzalez, E., Harris, N. L., & Duncan, L. M. (2000). Rapidly progressing mycosis fungoides presenting as follicular mucinosis. Journal of the American Academy of Dermatology, 43(4), 635-40.
Bonta MD, et al. Rapidly Progressing Mycosis Fungoides Presenting as Follicular Mucinosis. J Am Acad Dermatol. 2000;43(4):635-40. PubMed PMID: 11004619.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rapidly progressing mycosis fungoides presenting as follicular mucinosis. AU - Bonta,M D, AU - Tannous,Z S, AU - Demierre,M F, AU - Gonzalez,E, AU - Harris,N L, AU - Duncan,L M, PY - 2000/9/27/pubmed PY - 2001/2/28/medline PY - 2000/9/27/entrez SP - 635 EP - 40 JF - Journal of the American Academy of Dermatology JO - J Am Acad Dermatol VL - 43 IS - 4 N2 - Follicular mucinosis can occur as a primary idiopathic disorder or can arise in association with benign or malignant disease, most notably mycosis fungoides. We describe a patient with an aggressive folliculotropic variant of mycosis fungoides that initially presented as follicular mucinosis with alopecia. One month after the diagnosis of follicular mucinosis, a diagnosis of mycosis fungoides was made, and 3 months later inguinal lymph node involvement with mycosis fungoides developed. A skin biopsy specimen demonstrated prominent follicular mucinosis with folliculotropism of atypical cells and intrafollicular Pautrier's microabscesses. As demonstrated in this case, follicular mucinosis can be a presenting sign of rapidly progressive mycosis fungoides. In our review of follicular mucinosis and its association with mycosis fungoides, we found that the folliculotropic variant of mycosis fungoides appears more commonly to have an aggressive course than classic mycosis fungoides. SN - 0190-9622 UR - https://www.unboundmedicine.com/medline/citation/11004619/Rapidly_progressing_mycosis_fungoides_presenting_as_follicular_mucinosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0190-9622(00)76671-0 DB - PRIME DP - Unbound Medicine ER -