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Prospective study of major dietary patterns and risk of coronary heart disease in men.
Am J Clin Nutr. 2000 Oct; 72(4):912-21.AJ

Abstract

BACKGROUND

Previous studies on diet and coronary heart disease (CHD) focused primarily on individual nutrients or foods.

OBJECTIVE

We examined whether overall dietary patterns derived from a food-frequency questionnaire (FFQ) predict risk of CHD in men.

DESIGN

This was a prospective cohort study of 44875 men aged 40-75 y without diagnosed cardiovascular disease or cancer at baseline in 1986.

RESULTS

During 8 y of follow-up, we documented 1089 cases of CHD (nonfatal myocardial infarction and fatal CHD). Using factor analysis, we identified 2 major dietary patterns using dietary data collected through a 131-item FFQ. The first factor, which we labeled the "prudent pattern," was characterized by higher intake of vegetables, fruit, legumes, whole grains, fish, and poultry, whereas the second factor, the "Western pattern," was characterized by higher intake of red meat, processed meat, refined grains, sweets and dessert, French fries, and high-fat dairy products. After adjustment for age and CHD risk factors, the relative risks from the lowest to highest quintiles of the prudent pattern score were 1.0, 0. 87, 0.79, 0.75, and 0.70 (95% CI: 0.56, 0.86; P: for trend = 0.0009). In contrast, the relative risks across increasing quintiles of the Western pattern score were 1.0, 1.21, 1.36, 1.40, and 1.64 (95% CI: 1.24, 2.17; P: for trend < 0.0001). These associations persisted in subgroup analyses according to cigarette smoking, body mass index, and parental history of myocardial infarction.

CONCLUSIONS

These data suggest that major dietary patterns derived from the FFQ predict risk of CHD, independent of other lifestyle variables.

Authors+Show Affiliations

Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

11010931

Citation

Hu, F B., et al. "Prospective Study of Major Dietary Patterns and Risk of Coronary Heart Disease in Men." The American Journal of Clinical Nutrition, vol. 72, no. 4, 2000, pp. 912-21.
Hu FB, Rimm EB, Stampfer MJ, et al. Prospective study of major dietary patterns and risk of coronary heart disease in men. Am J Clin Nutr. 2000;72(4):912-21.
Hu, F. B., Rimm, E. B., Stampfer, M. J., Ascherio, A., Spiegelman, D., & Willett, W. C. (2000). Prospective study of major dietary patterns and risk of coronary heart disease in men. The American Journal of Clinical Nutrition, 72(4), 912-21.
Hu FB, et al. Prospective Study of Major Dietary Patterns and Risk of Coronary Heart Disease in Men. Am J Clin Nutr. 2000;72(4):912-21. PubMed PMID: 11010931.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prospective study of major dietary patterns and risk of coronary heart disease in men. AU - Hu,F B, AU - Rimm,E B, AU - Stampfer,M J, AU - Ascherio,A, AU - Spiegelman,D, AU - Willett,W C, PY - 2000/9/30/pubmed PY - 2000/10/21/medline PY - 2000/9/30/entrez SP - 912 EP - 21 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 72 IS - 4 N2 - BACKGROUND: Previous studies on diet and coronary heart disease (CHD) focused primarily on individual nutrients or foods. OBJECTIVE: We examined whether overall dietary patterns derived from a food-frequency questionnaire (FFQ) predict risk of CHD in men. DESIGN: This was a prospective cohort study of 44875 men aged 40-75 y without diagnosed cardiovascular disease or cancer at baseline in 1986. RESULTS: During 8 y of follow-up, we documented 1089 cases of CHD (nonfatal myocardial infarction and fatal CHD). Using factor analysis, we identified 2 major dietary patterns using dietary data collected through a 131-item FFQ. The first factor, which we labeled the "prudent pattern," was characterized by higher intake of vegetables, fruit, legumes, whole grains, fish, and poultry, whereas the second factor, the "Western pattern," was characterized by higher intake of red meat, processed meat, refined grains, sweets and dessert, French fries, and high-fat dairy products. After adjustment for age and CHD risk factors, the relative risks from the lowest to highest quintiles of the prudent pattern score were 1.0, 0. 87, 0.79, 0.75, and 0.70 (95% CI: 0.56, 0.86; P: for trend = 0.0009). In contrast, the relative risks across increasing quintiles of the Western pattern score were 1.0, 1.21, 1.36, 1.40, and 1.64 (95% CI: 1.24, 2.17; P: for trend < 0.0001). These associations persisted in subgroup analyses according to cigarette smoking, body mass index, and parental history of myocardial infarction. CONCLUSIONS: These data suggest that major dietary patterns derived from the FFQ predict risk of CHD, independent of other lifestyle variables. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/11010931/Prospective_study_of_major_dietary_patterns_and_risk_of_coronary_heart_disease_in_men_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/72.4.912 DB - PRIME DP - Unbound Medicine ER -