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Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome presenting as a primary calvarial lesion. Case report and review of the literature.
J Neurosurg 2000; 93(4):693-7JN

Abstract

The synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a recently described, currently evolving clinical entity that groups together several idiopathic disorders of bone and skin formerly described under a variety of names. Among the spectrum of possible locations for the bone lesions, there is no previous report in the literature of primary involvement of the skull vault. A patient with primary involvement of the calvaria in the setting of SAPHO syndrome is described here, which, to the authors' knowledge, is the first report of such localization. The clinically and radiologically benign evolution of the different stages of the bone lesions is presented. The authors suggest that the SAPHO syndrome should be considered in the differential diagnosis of lytic, sclerotic, or hyperostotic lesions of the skull, particularly before considering invasive diagnostic procedures.

Authors+Show Affiliations

Department of Neurological Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11014551

Citation

DiMeco, F, et al. "Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome Presenting as a Primary Calvarial Lesion. Case Report and Review of the Literature." Journal of Neurosurgery, vol. 93, no. 4, 2000, pp. 693-7.
DiMeco F, Clatterbuck RE, Li KW, et al. Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome presenting as a primary calvarial lesion. Case report and review of the literature. J Neurosurg. 2000;93(4):693-7.
DiMeco, F., Clatterbuck, R. E., Li, K. W., McCarthy, E. F., & Olivi, A. (2000). Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome presenting as a primary calvarial lesion. Case report and review of the literature. Journal of Neurosurgery, 93(4), pp. 693-7.
DiMeco F, et al. Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome Presenting as a Primary Calvarial Lesion. Case Report and Review of the Literature. J Neurosurg. 2000;93(4):693-7. PubMed PMID: 11014551.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome presenting as a primary calvarial lesion. Case report and review of the literature. AU - DiMeco,F, AU - Clatterbuck,R E, AU - Li,K W, AU - McCarthy,E F, AU - Olivi,A, PY - 2000/10/3/pubmed PY - 2000/10/21/medline PY - 2000/10/3/entrez SP - 693 EP - 7 JF - Journal of neurosurgery JO - J. Neurosurg. VL - 93 IS - 4 N2 - The synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a recently described, currently evolving clinical entity that groups together several idiopathic disorders of bone and skin formerly described under a variety of names. Among the spectrum of possible locations for the bone lesions, there is no previous report in the literature of primary involvement of the skull vault. A patient with primary involvement of the calvaria in the setting of SAPHO syndrome is described here, which, to the authors' knowledge, is the first report of such localization. The clinically and radiologically benign evolution of the different stages of the bone lesions is presented. The authors suggest that the SAPHO syndrome should be considered in the differential diagnosis of lytic, sclerotic, or hyperostotic lesions of the skull, particularly before considering invasive diagnostic procedures. SN - 0022-3085 UR - https://www.unboundmedicine.com/medline/citation/11014551/Synovitis_acne_pustulosis_hyperostosis_and_osteitis_syndrome_presenting_as_a_primary_calvarial_lesion__Case_report_and_review_of_the_literature_ L2 - https://thejns.org/doi/10.3171/jns.2000.93.4.0693 DB - PRIME DP - Unbound Medicine ER -