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Effect of carbon monoxide on maximal treadmill exercise. A study in normal persons.
Ann Intern Med. 1975 Oct; 83(4):496-9.AIM

Abstract

The effect of breathing 100 ppm of carbon monoxide versus compressed, purified air for 1 h on maximal treadmill exericse was studied (double-blind crossover design) in 10 middle-aged, healthy nonsmokers. The mean venous carboxyhemoglobin level significantly increased from 1.67% to 3.95% after breathing carbon monoxide (P less than 0.001) and significantly decreased from 1.63% to 1.30% after breathing compressed, purified air (P less than 0.001). The mean exercise time until exhaustion significantly decreased from 697.7 to 662.7 s after breathing carbon monoxide (P less than 0.001) and insignificantly increased from 694.9 s to 703.4 s after breathing compressed, purified air. Ischemic S-T segment depression larger than or equal to 1.0 mm after exercise occurred in 1 of 10 subjects after exercise following carbon monoxide inhalation. Increased carboxyhemoglobin levels of the magnitude encountered after smoking or heavy atmospheric pollution impair exercise performance in normal persons.

Authors

Aronow WS
No affiliation info available
Cassidy J
No affiliation info available

MeSH

AirBlood PressureCarbon MonoxideCarboxyhemoglobinClinical Trials as TopicExercise TestFemaleHeart RateHemoglobinsHumansMaleMiddle AgedTime Factors

Pub Type(s)

Clinical Trial
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

1101762

Citation

Aronow, W S., and J Cassidy. "Effect of Carbon Monoxide On Maximal Treadmill Exercise. a Study in Normal Persons." Annals of Internal Medicine, vol. 83, no. 4, 1975, pp. 496-9.
Aronow WS, Cassidy J. Effect of carbon monoxide on maximal treadmill exercise. A study in normal persons. Ann Intern Med. 1975;83(4):496-9.
Aronow, W. S., & Cassidy, J. (1975). Effect of carbon monoxide on maximal treadmill exercise. A study in normal persons. Annals of Internal Medicine, 83(4), 496-9.
Aronow WS, Cassidy J. Effect of Carbon Monoxide On Maximal Treadmill Exercise. a Study in Normal Persons. Ann Intern Med. 1975;83(4):496-9. PubMed PMID: 1101762.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of carbon monoxide on maximal treadmill exercise. A study in normal persons. AU - Aronow,W S, AU - Cassidy,J, PY - 1975/10/1/pubmed PY - 1975/10/1/medline PY - 1975/10/1/entrez SP - 496 EP - 9 JF - Annals of internal medicine JO - Ann Intern Med VL - 83 IS - 4 N2 - The effect of breathing 100 ppm of carbon monoxide versus compressed, purified air for 1 h on maximal treadmill exericse was studied (double-blind crossover design) in 10 middle-aged, healthy nonsmokers. The mean venous carboxyhemoglobin level significantly increased from 1.67% to 3.95% after breathing carbon monoxide (P less than 0.001) and significantly decreased from 1.63% to 1.30% after breathing compressed, purified air (P less than 0.001). The mean exercise time until exhaustion significantly decreased from 697.7 to 662.7 s after breathing carbon monoxide (P less than 0.001) and insignificantly increased from 694.9 s to 703.4 s after breathing compressed, purified air. Ischemic S-T segment depression larger than or equal to 1.0 mm after exercise occurred in 1 of 10 subjects after exercise following carbon monoxide inhalation. Increased carboxyhemoglobin levels of the magnitude encountered after smoking or heavy atmospheric pollution impair exercise performance in normal persons. SN - 0003-4819 UR - https://www.unboundmedicine.com/medline/citation/1101762/Effect_of_carbon_monoxide_on_maximal_treadmill_exercise__A_study_in_normal_persons_ DB - PRIME DP - Unbound Medicine ER -