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Pancreatic adenocarcinoma in a patient with Peutz-Jeghers syndrome: report of a case and literature review.
Hepatogastroenterology. 2000 Jul-Aug; 47(34):1159-61.H

Abstract

We present a rare case of pancreatic adenocarcinoma in a 47-year-old man with the Peutz-Jeghers syndrome. The patient underwent pancreatoduodenectomy with partial resection of the portal vein. We also review the current literature concerning Peutz-Jeghers syndrome associated with malignant tumors, especially pancreatic cancer. To our knowledge, this is the first report of a Peutz-Jeghers syndrome patient with pancreatic cancer having pancreatoduodenectomy and pathologically diagnosed with invasive ductal adenocarcinoma of the pancreas. The Peutz-Jeghers syndrome patients with pancreatic cancer were relatively young. As the pancreatic cancer in these patients was advanced and most were unresectable at diagnosis, the prognoses of these patients were extremely poor. Surgical resection offers the only chance for cure or long-term survival for Peutz-Jeghers syndrome patients, if the tumor is localized without distant metastasis. Therefore, screening even for young patients with Peutz-Jeghers syndrome is necessary for early detection of cancer.

Authors+Show Affiliations

First Department of Surgery, Nara Medical University, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

11020903

Citation

Hirao, S, et al. "Pancreatic Adenocarcinoma in a Patient With Peutz-Jeghers Syndrome: Report of a Case and Literature Review." Hepato-gastroenterology, vol. 47, no. 34, 2000, pp. 1159-61.
Hirao S, Sho M, Kanehiro H, et al. Pancreatic adenocarcinoma in a patient with Peutz-Jeghers syndrome: report of a case and literature review. Hepatogastroenterology. 2000;47(34):1159-61.
Hirao, S., Sho, M., Kanehiro, H., Hisanaga, M., Ikeda, N., Tsurui, H., Nakajima, Y., & Nakano, H. (2000). Pancreatic adenocarcinoma in a patient with Peutz-Jeghers syndrome: report of a case and literature review. Hepato-gastroenterology, 47(34), 1159-61.
Hirao S, et al. Pancreatic Adenocarcinoma in a Patient With Peutz-Jeghers Syndrome: Report of a Case and Literature Review. Hepatogastroenterology. 2000 Jul-Aug;47(34):1159-61. PubMed PMID: 11020903.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pancreatic adenocarcinoma in a patient with Peutz-Jeghers syndrome: report of a case and literature review. AU - Hirao,S, AU - Sho,M, AU - Kanehiro,H, AU - Hisanaga,M, AU - Ikeda,N, AU - Tsurui,H, AU - Nakajima,Y, AU - Nakano,H, PY - 2000/10/6/pubmed PY - 2001/3/3/medline PY - 2000/10/6/entrez SP - 1159 EP - 61 JF - Hepato-gastroenterology JO - Hepatogastroenterology VL - 47 IS - 34 N2 - We present a rare case of pancreatic adenocarcinoma in a 47-year-old man with the Peutz-Jeghers syndrome. The patient underwent pancreatoduodenectomy with partial resection of the portal vein. We also review the current literature concerning Peutz-Jeghers syndrome associated with malignant tumors, especially pancreatic cancer. To our knowledge, this is the first report of a Peutz-Jeghers syndrome patient with pancreatic cancer having pancreatoduodenectomy and pathologically diagnosed with invasive ductal adenocarcinoma of the pancreas. The Peutz-Jeghers syndrome patients with pancreatic cancer were relatively young. As the pancreatic cancer in these patients was advanced and most were unresectable at diagnosis, the prognoses of these patients were extremely poor. Surgical resection offers the only chance for cure or long-term survival for Peutz-Jeghers syndrome patients, if the tumor is localized without distant metastasis. Therefore, screening even for young patients with Peutz-Jeghers syndrome is necessary for early detection of cancer. SN - 0172-6390 UR - https://www.unboundmedicine.com/medline/citation/11020903/Pancreatic_adenocarcinoma_in_a_patient_with_Peutz_Jeghers_syndrome:_report_of_a_case_and_literature_review_ L2 - http://www.diseaseinfosearch.org/result/5695 DB - PRIME DP - Unbound Medicine ER -