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Tomato lycopene and its role in human health and chronic diseases.
CMAJ. 2000 Sep 19; 163(6):739-44.CMAJ

Abstract

Lycopene is a carotenoid that is present in tomatoes, processed tomato products and other fruits. It is one of the most potent antioxidants among dietary carotenoids. Dietary intake of tomatoes and tomato products containing lycopene has been shown to be associated with a decreased risk of chronic diseases, such as cancer and cardiovascular disease. Serum and tissue lycopene levels have been found to be inversely related to the incidence of several types of cancer, including breast cancer and prostate cancer. Although the antioxidant properties of lycopene are thought to be primarily responsible for its beneficial effects, evidence is accumulating to suggest that other mechanisms may also be involved. In this article we outline the possible mechanisms of action of lycopene and review the current understanding of its role in human health and disease prevention.

Authors+Show Affiliations

Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Ont.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

11022591

Citation

Agarwal, S, and A V. Rao. "Tomato Lycopene and Its Role in Human Health and Chronic Diseases." CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, vol. 163, no. 6, 2000, pp. 739-44.
Agarwal S, Rao AV. Tomato lycopene and its role in human health and chronic diseases. CMAJ. 2000;163(6):739-44.
Agarwal, S., & Rao, A. V. (2000). Tomato lycopene and its role in human health and chronic diseases. CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, 163(6), 739-44.
Agarwal S, Rao AV. Tomato Lycopene and Its Role in Human Health and Chronic Diseases. CMAJ. 2000 Sep 19;163(6):739-44. PubMed PMID: 11022591.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tomato lycopene and its role in human health and chronic diseases. AU - Agarwal,S, AU - Rao,A V, PY - 2000/10/7/pubmed PY - 2001/2/28/medline PY - 2000/10/7/entrez SP - 739 EP - 44 JF - CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne JO - CMAJ VL - 163 IS - 6 N2 - Lycopene is a carotenoid that is present in tomatoes, processed tomato products and other fruits. It is one of the most potent antioxidants among dietary carotenoids. Dietary intake of tomatoes and tomato products containing lycopene has been shown to be associated with a decreased risk of chronic diseases, such as cancer and cardiovascular disease. Serum and tissue lycopene levels have been found to be inversely related to the incidence of several types of cancer, including breast cancer and prostate cancer. Although the antioxidant properties of lycopene are thought to be primarily responsible for its beneficial effects, evidence is accumulating to suggest that other mechanisms may also be involved. In this article we outline the possible mechanisms of action of lycopene and review the current understanding of its role in human health and disease prevention. SN - 0820-3946 UR - https://www.unboundmedicine.com/medline/citation/11022591/Tomato_lycopene_and_its_role_in_human_health_and_chronic_diseases_ L2 - http://www.cmaj.ca/cgi/pmidlookup?view=long&pmid=11022591 DB - PRIME DP - Unbound Medicine ER -