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[Gastric polyps in pernicious anemia: indications for polypectomy].
Dtsch Med Wochenschr 2000; 125(36):1035-8DM

Abstract

HISTORY AND CLINICAL FINDINGS

A 54-year-old man was admitted to hospital with dyspnoea, giddiness, lack of appetite and burning sensation in the tongue for 3 years. Gastritis was known from his history. Clinical examination showed jaundice, glossitis, systolic murmur and pallhypesthesia of both legs.

INVESTIGATIONS

Blood and bone marrow investigations revealed pernicious anaemia. At gastroscopy, fundal gastritis was diagnosed and two small polyps of the fundus were removed. Histologically, one of the two polyps turned out to be a gastric carcinoid type 1 (according to [16]). Additional investigations (x-ray, ultrasound of the abdomen, somatostatin-receptor scintigraphy) did not find any metastases.

TREATMENT AND COURSE

With the diagnosis of a pernicious anaemia the patient was treated with vitamin B12. The original symptoms and the anaemia disappeared. Additional therapy of the gastric carcinoid was not necessary. One year after beginning of the treatment, no signs of the gastric carcinoid were found.

CONCLUSION

In gastric polyps of patients with pernicious anemia neoplastic transformations will often be found. That is why polypectomy should always be done. The best therapy of the gastric carcinoids type 1, which are the most frequently gastric carcinoids, is endoscopic tumour removal. Surgery is the treatment of choice only for gastric carcinoids type 2 to 4. Concerning quality of life and costs, endoscopic treatment is better for patients with gastric carcinoids type 1 than conventional surgical therapy.

Authors+Show Affiliations

Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Universitätsklinikums Charité, Humboldt-Universität zu Berlin.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Comparative Study
English Abstract
Journal Article

Language

ger

PubMed ID

11022599

Citation

Rickes, S, et al. "[Gastric Polyps in Pernicious Anemia: Indications for Polypectomy]." Deutsche Medizinische Wochenschrift (1946), vol. 125, no. 36, 2000, pp. 1035-8.
Rickes S, Gerl H, Lochs H. [Gastric polyps in pernicious anemia: indications for polypectomy]. Dtsch Med Wochenschr. 2000;125(36):1035-8.
Rickes, S., Gerl, H., & Lochs, H. (2000). [Gastric polyps in pernicious anemia: indications for polypectomy]. Deutsche Medizinische Wochenschrift (1946), 125(36), pp. 1035-8.
Rickes S, Gerl H, Lochs H. [Gastric Polyps in Pernicious Anemia: Indications for Polypectomy]. Dtsch Med Wochenschr. 2000 Sep 8;125(36):1035-8. PubMed PMID: 11022599.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Gastric polyps in pernicious anemia: indications for polypectomy]. AU - Rickes,S, AU - Gerl,H, AU - Lochs,H, PY - 2000/10/7/pubmed PY - 2000/10/21/medline PY - 2000/10/7/entrez SP - 1035 EP - 8 JF - Deutsche medizinische Wochenschrift (1946) JO - Dtsch. Med. Wochenschr. VL - 125 IS - 36 N2 - HISTORY AND CLINICAL FINDINGS: A 54-year-old man was admitted to hospital with dyspnoea, giddiness, lack of appetite and burning sensation in the tongue for 3 years. Gastritis was known from his history. Clinical examination showed jaundice, glossitis, systolic murmur and pallhypesthesia of both legs. INVESTIGATIONS: Blood and bone marrow investigations revealed pernicious anaemia. At gastroscopy, fundal gastritis was diagnosed and two small polyps of the fundus were removed. Histologically, one of the two polyps turned out to be a gastric carcinoid type 1 (according to [16]). Additional investigations (x-ray, ultrasound of the abdomen, somatostatin-receptor scintigraphy) did not find any metastases. TREATMENT AND COURSE: With the diagnosis of a pernicious anaemia the patient was treated with vitamin B12. The original symptoms and the anaemia disappeared. Additional therapy of the gastric carcinoid was not necessary. One year after beginning of the treatment, no signs of the gastric carcinoid were found. CONCLUSION: In gastric polyps of patients with pernicious anemia neoplastic transformations will often be found. That is why polypectomy should always be done. The best therapy of the gastric carcinoids type 1, which are the most frequently gastric carcinoids, is endoscopic tumour removal. Surgery is the treatment of choice only for gastric carcinoids type 2 to 4. Concerning quality of life and costs, endoscopic treatment is better for patients with gastric carcinoids type 1 than conventional surgical therapy. SN - 0012-0472 UR - https://www.unboundmedicine.com/medline/citation/11022599/[Gastric_polyps_in_pernicious_anemia:_indications_for_polypectomy]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-7207 DB - PRIME DP - Unbound Medicine ER -