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Shosaiko-to and other Kampo (Japanese herbal) medicines: a review of their immunomodulatory activities.
J Ethnopharmacol 2000; 73(1-2):1-13JE

Abstract

The use of alternative medicine, including consumption of herbal products and dietary supplements, has been increasing substantially both in the United States and in Western Europe. One area that is garnering increased attention is the use of Oriental Medicine including Kampo, or Japanese herbal medicine. Herein, we review representative examples of research available on the most common use of Kampo medicinals, namely to improve the immune response. We also provide an extensive background on the history of Kampo. There are more than 210 different Kampo formulae used in Japan and most uses of Kampo are to modulate the immune response, i.e. to improve immunity. We have extracted data on seven common Kampo medicinals, and the data are reviewed with respect to in vitro and in vivo activities for both humans and experimental animals; the ingredients as well as the problems with classification of these materials are presented. Research suggests that Kampo herbals are biologically active and may have therapeutic potential. While it is believed that Kampo medicines have few side effects, there is a paucity of data on their toxicity as well as a relative lack of knowledge of the bioactive constituents and potential drug interactions of these agents.

Authors+Show Affiliations

Department of Internal Medicine, Division of Rheumatology, Allergy and Clinical Immunology, School of Medicine, University of California, TB 192, Davis, CA 95616, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

11025134

Citation

Borchers, A T., et al. "Shosaiko-to and Other Kampo (Japanese Herbal) Medicines: a Review of Their Immunomodulatory Activities." Journal of Ethnopharmacology, vol. 73, no. 1-2, 2000, pp. 1-13.
Borchers AT, Sakai S, Henderson GL, et al. Shosaiko-to and other Kampo (Japanese herbal) medicines: a review of their immunomodulatory activities. J Ethnopharmacol. 2000;73(1-2):1-13.
Borchers, A. T., Sakai, S., Henderson, G. L., Harkey, M. R., Keen, C. L., Stern, J. S., ... Gershwin, M. E. (2000). Shosaiko-to and other Kampo (Japanese herbal) medicines: a review of their immunomodulatory activities. Journal of Ethnopharmacology, 73(1-2), pp. 1-13.
Borchers AT, et al. Shosaiko-to and Other Kampo (Japanese Herbal) Medicines: a Review of Their Immunomodulatory Activities. J Ethnopharmacol. 2000;73(1-2):1-13. PubMed PMID: 11025134.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Shosaiko-to and other Kampo (Japanese herbal) medicines: a review of their immunomodulatory activities. AU - Borchers,A T, AU - Sakai,S, AU - Henderson,G L, AU - Harkey,M R, AU - Keen,C L, AU - Stern,J S, AU - Terasawa,K, AU - Gershwin,M E, PY - 2000/10/12/pubmed PY - 2001/2/28/medline PY - 2000/10/12/entrez SP - 1 EP - 13 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 73 IS - 1-2 N2 - The use of alternative medicine, including consumption of herbal products and dietary supplements, has been increasing substantially both in the United States and in Western Europe. One area that is garnering increased attention is the use of Oriental Medicine including Kampo, or Japanese herbal medicine. Herein, we review representative examples of research available on the most common use of Kampo medicinals, namely to improve the immune response. We also provide an extensive background on the history of Kampo. There are more than 210 different Kampo formulae used in Japan and most uses of Kampo are to modulate the immune response, i.e. to improve immunity. We have extracted data on seven common Kampo medicinals, and the data are reviewed with respect to in vitro and in vivo activities for both humans and experimental animals; the ingredients as well as the problems with classification of these materials are presented. Research suggests that Kampo herbals are biologically active and may have therapeutic potential. While it is believed that Kampo medicines have few side effects, there is a paucity of data on their toxicity as well as a relative lack of knowledge of the bioactive constituents and potential drug interactions of these agents. SN - 0378-8741 UR - https://www.unboundmedicine.com/medline/citation/11025134/Shosaiko_to_and_other_Kampo__Japanese_herbal__medicines:_a_review_of_their_immunomodulatory_activities_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378-8741(00)00334-2 DB - PRIME DP - Unbound Medicine ER -