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Using ferritin levels to determine iron-deficiency anemia in pregnancy.
J Fam Pract. 2000 Sep; 49(9):829-32.JF

Abstract

BACKGROUND

Standard obstetrical practice has included iron therapy for patients with anemia without requiring the determination of iron deficiency. However, the proportion of pregnant women with anemia who have such a deficiency may be relatively modest. We instituted a practice protocol using serum ferritin levels to determine the proportion of women undergoing prenatal care who had both anemia and iron deficiency.

METHODS

We evaluated consecutive women entering prenatal care. Those with anemia (hemoglobin level <11 mg/dL) underwent testing for serum ferritin level and other hematologic variables.

RESULTS

A total of 182 patients entered prenatal care. Hemoglobin data were available for 173 (95%). Thirty-eight (22%) had anemia (hemoglobin level <11 mg/dL); 1 of those women was excluded from the study. Using a ferritin level of 12 mg per dL as the cutoff for iron deficiency, 54% (20) of the 37 remaining patients with anemia had an iron deficiency, and 46% (17) had anemia not related to such a deficiency. Use of hematologic indices provided on complete blood count were not useful in predicting iron deficiency based on serum ferritin levels.

CONCLUSIONS

In our population of prenatal patients with anemia, only approximately half had an iron deficiency. Diagnostic and therapeutic approaches to screening for anemia in pregnancy should be reconsidered and further evaluated.

Authors+Show Affiliations

Family and Community Medicine Residency Program of Pennsylvania State University/Good Samaritan Hospital, Lebanon, USA. alper@earthlink.netNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11032208

Citation

Alper, B S., et al. "Using Ferritin Levels to Determine Iron-deficiency Anemia in Pregnancy." The Journal of Family Practice, vol. 49, no. 9, 2000, pp. 829-32.
Alper BS, Kimber R, Reddy AK. Using ferritin levels to determine iron-deficiency anemia in pregnancy. J Fam Pract. 2000;49(9):829-32.
Alper, B. S., Kimber, R., & Reddy, A. K. (2000). Using ferritin levels to determine iron-deficiency anemia in pregnancy. The Journal of Family Practice, 49(9), 829-32.
Alper BS, Kimber R, Reddy AK. Using Ferritin Levels to Determine Iron-deficiency Anemia in Pregnancy. J Fam Pract. 2000;49(9):829-32. PubMed PMID: 11032208.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Using ferritin levels to determine iron-deficiency anemia in pregnancy. AU - Alper,B S, AU - Kimber,R, AU - Reddy,A K, PY - 2000/10/14/pubmed PY - 2001/2/28/medline PY - 2000/10/14/entrez SP - 829 EP - 32 JF - The Journal of family practice JO - J Fam Pract VL - 49 IS - 9 N2 - BACKGROUND: Standard obstetrical practice has included iron therapy for patients with anemia without requiring the determination of iron deficiency. However, the proportion of pregnant women with anemia who have such a deficiency may be relatively modest. We instituted a practice protocol using serum ferritin levels to determine the proportion of women undergoing prenatal care who had both anemia and iron deficiency. METHODS: We evaluated consecutive women entering prenatal care. Those with anemia (hemoglobin level <11 mg/dL) underwent testing for serum ferritin level and other hematologic variables. RESULTS: A total of 182 patients entered prenatal care. Hemoglobin data were available for 173 (95%). Thirty-eight (22%) had anemia (hemoglobin level <11 mg/dL); 1 of those women was excluded from the study. Using a ferritin level of 12 mg per dL as the cutoff for iron deficiency, 54% (20) of the 37 remaining patients with anemia had an iron deficiency, and 46% (17) had anemia not related to such a deficiency. Use of hematologic indices provided on complete blood count were not useful in predicting iron deficiency based on serum ferritin levels. CONCLUSIONS: In our population of prenatal patients with anemia, only approximately half had an iron deficiency. Diagnostic and therapeutic approaches to screening for anemia in pregnancy should be reconsidered and further evaluated. SN - 0094-3509 UR - https://www.unboundmedicine.com/medline/citation/11032208/Using_ferritin_levels_to_determine_iron_deficiency_anemia_in_pregnancy_ DB - PRIME DP - Unbound Medicine ER -