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Deficit in sensory motor processing in depression and Alzheimer's disease: a study with EMG and event related potentials.
Electromyogr Clin Neurophysiol. 2000 Sep; 40(6):357-63.EC

Abstract

Event related potentials have been examined in depression and Alzheimer disease like clinical utility. To evaluate the influence of visual and auditory stimuli on the P300 latency we studied 12 patients with major depression, 12 patients with Alzheimer disease and 12 normal subjects. The experimental tasks applied was, first a series of 300 auditory stimuli, 255 (85%), with tones of 1,000 Hz, and considered as the frequent stimulus, whereas 45 (15%) were tones of 2,000 Hz and referred as the rare stimulus. A second series of 300 visual stimuli, 255 (85%) that were black circles on a white background, and considered the frequent stimulus (9 cm diameter, 200 ms duration), whereas 45 (15%) were black squares on a white background and referred as the rare stimulus (9 cm diameter, 200 ms duration) in the centre of a computer screen. The results show an increase of P300 latency in depressive and Alzheimer patients during auditory and visual tasks. Differences were found in reaction time to visual or auditory stimuli in Alzheimer disease. These results are consistent with an impairment in brain function in depressive patients that is associated with cortical hypoactivity and deficits in perceptive, auditory or visual, functions, whereas deterioration in Alzheimer's disease is sensorymotor, according to the slowness latency in the reaction time.

Authors+Show Affiliations

Departamento de Psiquiatría y Psicología Médica, Facultad de Medicina, Universidad Complutense de Madrid, España.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11039120

Citation

Ortiz Alonso, T, et al. "Deficit in Sensory Motor Processing in Depression and Alzheimer's Disease: a Study With EMG and Event Related Potentials." Electromyography and Clinical Neurophysiology, vol. 40, no. 6, 2000, pp. 357-63.
Ortiz Alonso T, López-Ibor MI, Martínez Castillo E, et al. Deficit in sensory motor processing in depression and Alzheimer's disease: a study with EMG and event related potentials. Electromyogr Clin Neurophysiol. 2000;40(6):357-63.
Ortiz Alonso, T., López-Ibor, M. I., Martínez Castillo, E., Fernández Lucas, A., Maestú Unturbe, F., & López-Ibor, J. J. (2000). Deficit in sensory motor processing in depression and Alzheimer's disease: a study with EMG and event related potentials. Electromyography and Clinical Neurophysiology, 40(6), 357-63.
Ortiz Alonso T, et al. Deficit in Sensory Motor Processing in Depression and Alzheimer's Disease: a Study With EMG and Event Related Potentials. Electromyogr Clin Neurophysiol. 2000;40(6):357-63. PubMed PMID: 11039120.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Deficit in sensory motor processing in depression and Alzheimer's disease: a study with EMG and event related potentials. AU - Ortiz Alonso,T, AU - López-Ibor,M I, AU - Martínez Castillo,E, AU - Fernández Lucas,A, AU - Maestú Unturbe,F, AU - López-Ibor,J J, PY - 2000/10/20/pubmed PY - 2001/3/3/medline PY - 2000/10/20/entrez SP - 357 EP - 63 JF - Electromyography and clinical neurophysiology JO - Electromyogr Clin Neurophysiol VL - 40 IS - 6 N2 - Event related potentials have been examined in depression and Alzheimer disease like clinical utility. To evaluate the influence of visual and auditory stimuli on the P300 latency we studied 12 patients with major depression, 12 patients with Alzheimer disease and 12 normal subjects. The experimental tasks applied was, first a series of 300 auditory stimuli, 255 (85%), with tones of 1,000 Hz, and considered as the frequent stimulus, whereas 45 (15%) were tones of 2,000 Hz and referred as the rare stimulus. A second series of 300 visual stimuli, 255 (85%) that were black circles on a white background, and considered the frequent stimulus (9 cm diameter, 200 ms duration), whereas 45 (15%) were black squares on a white background and referred as the rare stimulus (9 cm diameter, 200 ms duration) in the centre of a computer screen. The results show an increase of P300 latency in depressive and Alzheimer patients during auditory and visual tasks. Differences were found in reaction time to visual or auditory stimuli in Alzheimer disease. These results are consistent with an impairment in brain function in depressive patients that is associated with cortical hypoactivity and deficits in perceptive, auditory or visual, functions, whereas deterioration in Alzheimer's disease is sensorymotor, according to the slowness latency in the reaction time. SN - 0301-150X UR - https://www.unboundmedicine.com/medline/citation/11039120/Deficit_in_sensory_motor_processing_in_depression_and_Alzheimer's_disease:_a_study_with_EMG_and_event_related_potentials_ L2 - http://www.diseaseinfosearch.org/result/2199 DB - PRIME DP - Unbound Medicine ER -