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Atypical ductal hyperplasia and ductal carcinoma in situ as revealed by large-core needle breast biopsy: results of surgical excision.
AJR Am J Roentgenol. 2000 Nov; 175(5):1341-6.AA

Abstract

OBJECTIVE

This investigation compares the frequency of histologic underestimation of breast carcinoma that occurs when a large-core needle biopsy reveals atypical ductal hyperplasia or ductal carcinoma in situ with the automated 14-gauge needle, the 14-gauge directional vacuum-assisted biopsy device, and the 11-gauge directional vacuum-assisted biopsy device.

SUBJECTS AND METHODS

Evaluation of 428 large-core needle biopsies yielding atypical ductal hyperplasia (139 lesions) or ductal carcinoma in situ (289 lesions) was performed. The results of subsequent surgical excision were retrospectively compared with the needle biopsy results.

RESULTS

For lesions initially diagnosed as ductal carcinoma in situ, underestimation of invasive ductal carcinoma was significantly less frequent using the 11-gauge directional vacuum-assisted biopsy device when compared with the automated 14-gauge needle (10% versus 21%, p < 0.05) but was not significantly less frequent when compared with the 14-gauge directional vacuum-assisted device (10% versus 17%, p > 0.1). For lesions diagnosed initially as atypical ductal hyperplasia, underestimation of ductal carcinoma in situ and invasive ductal carcinoma was significantly less frequent using the 11-gauge directional vacuum-assisted biopsy device compared with the 14-gauge directional vacuum-assisted device (19% versus 39%, p = 0. 025) and with the automated 14-gauge needle (19% versus 44%, p = 0. 01).

CONCLUSION

The frequency of histologic underestimation of breast carcinoma in lesions initially diagnosed as atypical ductal hyperplasia or ductal carcinoma in situ using large-core needle biopsy is substantially lower with the 11-gauge directional vacuum-assisted device than with the automated 14-gauge needle and with the 14-gauge directional vacuum-assisted device.

Authors+Show Affiliations

Darling ML
Department of Radiology, Brigham and Women's Hospital, 75 Francis St., Boston, MA 02115, USA.
Smith DN
No affiliation info available
Lester SC
No affiliation info available
Kaelin C
No affiliation info available
Selland DL
No affiliation info available
Denison CM
No affiliation info available
DiPiro PJ
No affiliation info available
Rose DI
No affiliation info available
Rhei E
No affiliation info available
Meyer JE
No affiliation info available

MeSH

AdultAgedAged, 80 and overAutomationBiopsy, NeedleBreastCalcinosisCarcinoma in SituCarcinoma, Ductal, BreastChi-Square DistributionEquipment DesignFemaleFollow-Up StudiesHumansHyperplasiaMiddle AgedNeoplasm InvasivenessRetrospective StudiesStereotaxic TechniquesUltrasonography, InterventionalUltrasonography, MammaryVacuum

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article

Language

eng

PubMed ID

11044038

Citation

Darling, M L., et al. "Atypical Ductal Hyperplasia and Ductal Carcinoma in Situ as Revealed By Large-core Needle Breast Biopsy: Results of Surgical Excision." AJR. American Journal of Roentgenology, vol. 175, no. 5, 2000, pp. 1341-6.
Darling ML, Smith DN, Lester SC, et al. Atypical ductal hyperplasia and ductal carcinoma in situ as revealed by large-core needle breast biopsy: results of surgical excision. AJR Am J Roentgenol. 2000;175(5):1341-6.
Darling, M. L., Smith, D. N., Lester, S. C., Kaelin, C., Selland, D. L., Denison, C. M., DiPiro, P. J., Rose, D. I., Rhei, E., & Meyer, J. E. (2000). Atypical ductal hyperplasia and ductal carcinoma in situ as revealed by large-core needle breast biopsy: results of surgical excision. AJR. American Journal of Roentgenology, 175(5), 1341-6.
Darling ML, et al. Atypical Ductal Hyperplasia and Ductal Carcinoma in Situ as Revealed By Large-core Needle Breast Biopsy: Results of Surgical Excision. AJR Am J Roentgenol. 2000;175(5):1341-6. PubMed PMID: 11044038.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Atypical ductal hyperplasia and ductal carcinoma in situ as revealed by large-core needle breast biopsy: results of surgical excision. AU - Darling,M L, AU - Smith,D N, AU - Lester,S C, AU - Kaelin,C, AU - Selland,D L, AU - Denison,C M, AU - DiPiro,P J, AU - Rose,D I, AU - Rhei,E, AU - Meyer,J E, PY - 2000/10/24/pubmed PY - 2001/2/28/medline PY - 2000/10/24/entrez SP - 1341 EP - 6 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 175 IS - 5 N2 - OBJECTIVE: This investigation compares the frequency of histologic underestimation of breast carcinoma that occurs when a large-core needle biopsy reveals atypical ductal hyperplasia or ductal carcinoma in situ with the automated 14-gauge needle, the 14-gauge directional vacuum-assisted biopsy device, and the 11-gauge directional vacuum-assisted biopsy device. SUBJECTS AND METHODS: Evaluation of 428 large-core needle biopsies yielding atypical ductal hyperplasia (139 lesions) or ductal carcinoma in situ (289 lesions) was performed. The results of subsequent surgical excision were retrospectively compared with the needle biopsy results. RESULTS: For lesions initially diagnosed as ductal carcinoma in situ, underestimation of invasive ductal carcinoma was significantly less frequent using the 11-gauge directional vacuum-assisted biopsy device when compared with the automated 14-gauge needle (10% versus 21%, p < 0.05) but was not significantly less frequent when compared with the 14-gauge directional vacuum-assisted device (10% versus 17%, p > 0.1). For lesions diagnosed initially as atypical ductal hyperplasia, underestimation of ductal carcinoma in situ and invasive ductal carcinoma was significantly less frequent using the 11-gauge directional vacuum-assisted biopsy device compared with the 14-gauge directional vacuum-assisted device (19% versus 39%, p = 0. 025) and with the automated 14-gauge needle (19% versus 44%, p = 0. 01). CONCLUSION: The frequency of histologic underestimation of breast carcinoma in lesions initially diagnosed as atypical ductal hyperplasia or ductal carcinoma in situ using large-core needle biopsy is substantially lower with the 11-gauge directional vacuum-assisted device than with the automated 14-gauge needle and with the 14-gauge directional vacuum-assisted device. SN - 0361-803X UR - https://www.unboundmedicine.com/medline/citation/11044038/Atypical_ductal_hyperplasia_and_ductal_carcinoma_in_situ_as_revealed_by_large_core_needle_breast_biopsy:_results_of_surgical_excision_ DB - PRIME DP - Unbound Medicine ER -