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Prospective study of the usefulness of sputum Gram stain in the initial approach to community-acquired pneumonia requiring hospitalization.
Clin Infect Dis. 2000 Oct; 31(4):869-74.CI

Abstract

From February 1995 through May 1997, we prospectively studied 533 patients with community-acquired pneumonia requiring hospitalization in order to assess the current usefulness of sputum Gram stain in guiding the etiologic diagnosis and initial antibiotic therapy when applied routinely. Sputum samples of good quality were obtained in 210 (39%) patients, 175 of whom showed a predominant morphotype. Sensitivity and specificity of Gram stain for the diagnosis of pneumococcal pneumonia were 57% and 97%, respectively; the corresponding values for Haemophilus influenzae pneumonia were 82% and 99%. Patients with a predominant morphotype were more frequently treated with monotherapy than were patients without a demonstrative sputum sample (89% vs. 75%; P<.001). Analysis of our data shows that a good-quality sputum sample can be obtained from a substantial number of patients with community-acquired pneumonia. Gram stain was highly specific for the diagnosis of pneumococcal and H. influenzae pneumonia and may be useful in guiding pathogen-oriented antimicrobial therapy.

Authors+Show Affiliations

Infectious Disease, Microbiology and Respiratory Services, Ciutat Sanitària i Universitària de Bellvitge, University of Barcelona, l'Hospitalet de Llobregat, Barcelona, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11049763

Citation

Rosón, B, et al. "Prospective Study of the Usefulness of Sputum Gram Stain in the Initial Approach to Community-acquired Pneumonia Requiring Hospitalization." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 31, no. 4, 2000, pp. 869-74.
Rosón B, Carratalà J, Verdaguer R, et al. Prospective study of the usefulness of sputum Gram stain in the initial approach to community-acquired pneumonia requiring hospitalization. Clin Infect Dis. 2000;31(4):869-74.
Rosón, B., Carratalà, J., Verdaguer, R., Dorca, J., Manresa, F., & Gudiol, F. (2000). Prospective study of the usefulness of sputum Gram stain in the initial approach to community-acquired pneumonia requiring hospitalization. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 31(4), 869-74.
Rosón B, et al. Prospective Study of the Usefulness of Sputum Gram Stain in the Initial Approach to Community-acquired Pneumonia Requiring Hospitalization. Clin Infect Dis. 2000;31(4):869-74. PubMed PMID: 11049763.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prospective study of the usefulness of sputum Gram stain in the initial approach to community-acquired pneumonia requiring hospitalization. AU - Rosón,B, AU - Carratalà,J, AU - Verdaguer,R, AU - Dorca,J, AU - Manresa,F, AU - Gudiol,F, Y1 - 2000/10/12/ PY - 1999/11/30/received PY - 2000/02/28/revised PY - 2000/10/26/pubmed PY - 2001/3/3/medline PY - 2000/10/26/entrez SP - 869 EP - 74 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin Infect Dis VL - 31 IS - 4 N2 - From February 1995 through May 1997, we prospectively studied 533 patients with community-acquired pneumonia requiring hospitalization in order to assess the current usefulness of sputum Gram stain in guiding the etiologic diagnosis and initial antibiotic therapy when applied routinely. Sputum samples of good quality were obtained in 210 (39%) patients, 175 of whom showed a predominant morphotype. Sensitivity and specificity of Gram stain for the diagnosis of pneumococcal pneumonia were 57% and 97%, respectively; the corresponding values for Haemophilus influenzae pneumonia were 82% and 99%. Patients with a predominant morphotype were more frequently treated with monotherapy than were patients without a demonstrative sputum sample (89% vs. 75%; P<.001). Analysis of our data shows that a good-quality sputum sample can be obtained from a substantial number of patients with community-acquired pneumonia. Gram stain was highly specific for the diagnosis of pneumococcal and H. influenzae pneumonia and may be useful in guiding pathogen-oriented antimicrobial therapy. SN - 1058-4838 UR - https://www.unboundmedicine.com/medline/citation/11049763/Prospective_study_of_the_usefulness_of_sputum_Gram_stain_in_the_initial_approach_to_community_acquired_pneumonia_requiring_hospitalization_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1086/318151 DB - PRIME DP - Unbound Medicine ER -