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Topical fluoroquinolones for eye and ear.
Am Fam Physician. 2000 Oct 15; 62(8):1870-6.AF

Abstract

Topical fluoroquinolones are now available for use in the eye and ear. Their broad spectrum of activity includes the common eye and ear pathogens Staphylococcus aureus and Pseudomonas aeruginosa. For the treatment of acute otitis externa, these agents are as effective as previously available otic preparations. For the treatment of otitis media with tympanic membrane perforation, topical fluoroquinolones are effective and safe. These preparations are approved for use in children, and lack of ototoxicity permits prolonged administration when necessary. Topical fluoroquinolones are not appropriate for the treatment of uncomplicated conjunctivitis where narrower spectrum agents suffice; they represent a simplified regimen for the treatment of bacterial keratitis (corneal ulcers). When administered topically, fluoroquinolones are well tolerated and offer convenient dosing schedules. Currently, bacterial resistance appears limited.

Authors+Show Affiliations

University of Massachusetts Medical School, Worcester, USA. NancyMorden@compuserve.comNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

11057842

Citation

Morden, N E., and E M. Berke. "Topical Fluoroquinolones for Eye and Ear." American Family Physician, vol. 62, no. 8, 2000, pp. 1870-6.
Morden NE, Berke EM. Topical fluoroquinolones for eye and ear. Am Fam Physician. 2000;62(8):1870-6.
Morden, N. E., & Berke, E. M. (2000). Topical fluoroquinolones for eye and ear. American Family Physician, 62(8), 1870-6.
Morden NE, Berke EM. Topical Fluoroquinolones for Eye and Ear. Am Fam Physician. 2000 Oct 15;62(8):1870-6. PubMed PMID: 11057842.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Topical fluoroquinolones for eye and ear. AU - Morden,N E, AU - Berke,E M, PY - 2000/11/1/pubmed PY - 2001/2/28/medline PY - 2000/11/1/entrez SP - 1870 EP - 6 JF - American family physician JO - Am Fam Physician VL - 62 IS - 8 N2 - Topical fluoroquinolones are now available for use in the eye and ear. Their broad spectrum of activity includes the common eye and ear pathogens Staphylococcus aureus and Pseudomonas aeruginosa. For the treatment of acute otitis externa, these agents are as effective as previously available otic preparations. For the treatment of otitis media with tympanic membrane perforation, topical fluoroquinolones are effective and safe. These preparations are approved for use in children, and lack of ototoxicity permits prolonged administration when necessary. Topical fluoroquinolones are not appropriate for the treatment of uncomplicated conjunctivitis where narrower spectrum agents suffice; they represent a simplified regimen for the treatment of bacterial keratitis (corneal ulcers). When administered topically, fluoroquinolones are well tolerated and offer convenient dosing schedules. Currently, bacterial resistance appears limited. SN - 0002-838X UR - https://www.unboundmedicine.com/medline/citation/11057842/Topical_fluoroquinolones_for_eye_and_ear_ L2 - https://www.aafp.org/link_out?pmid=11057842 DB - PRIME DP - Unbound Medicine ER -