Tags

Type your tag names separated by a space and hit enter

[Evaluation of serum sialic acid concentration in chronic renal failure children on continuous ambulatory peritoneal dialysis and hemodialysis].
Pol Merkur Lekarski. 2000 Jul; 8(49):459-61.PM

Abstract

In various pathological conditions elevated serum sialic acid level, as the result of increased metabolism of glycoproteins and glycolipids, is observed. The study aimed at the evaluation of sialic acid concentration in serum of children on continuous ambulatory peritoneal dialysis (CAPD) and maintenance haemodialysis (HD). Examination was performed in 27 end-stage renal disease (ESRD) children including 11 on CAPD, 16 on HD treatment. Ten healthy children served as the control group (K). In CAPD group assessment was carried out during the routine monthly check up, in HD group--before (HD-1) and after (HD-2) dialysis session. Sialic acid concentration was determined using method of Shamberger. In CAPD children we obtained significantly increased serum sialic acid concentration comparing to controls and HD children. Increased serum sialic acid concentration was also found in HD children comparing to controls. There was no significant difference between the sialic acid concentrations before and after dialysis session. Analysis of correlation revealed positive correlation of sialic acid concentration with haemoglobin concentration and hematocrit in CAPD group. In children on HD treatment we showed positive correlation of sialic acid level with renal replacement therapy duration and creatinine concentration after HD. Elevated serum sialic acid concentration in dialysed children could be the result of non-specific organism response, characterised by tissue and organ damage, towards the materials of extracorporeal circulation (HD) or the presence of dialysis solution in peritoneal cavity (CAPD).

Authors+Show Affiliations

Katedry i Kliniki Nefrologii, Endokrynologii i Chorób Metabolicznych Wieku Dzieciecego Slaskiej AM w Zabrzu.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

pol

PubMed ID

11070713

Citation

Szprynger, K, et al. "[Evaluation of Serum Sialic Acid Concentration in Chronic Renal Failure Children On Continuous Ambulatory Peritoneal Dialysis and Hemodialysis]." Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego, vol. 8, no. 49, 2000, pp. 459-61.
Szprynger K, Szczepańska M, Mazur B, et al. [Evaluation of serum sialic acid concentration in chronic renal failure children on continuous ambulatory peritoneal dialysis and hemodialysis]. Pol Merkur Lekarski. 2000;8(49):459-61.
Szprynger, K., Szczepańska, M., Mazur, B., Dyduch, A., Zwolińska, D., Morawiec-Knysak, A., & Makulska, I. (2000). [Evaluation of serum sialic acid concentration in chronic renal failure children on continuous ambulatory peritoneal dialysis and hemodialysis]. Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego, 8(49), 459-61.
Szprynger K, et al. [Evaluation of Serum Sialic Acid Concentration in Chronic Renal Failure Children On Continuous Ambulatory Peritoneal Dialysis and Hemodialysis]. Pol Merkur Lekarski. 2000;8(49):459-61. PubMed PMID: 11070713.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Evaluation of serum sialic acid concentration in chronic renal failure children on continuous ambulatory peritoneal dialysis and hemodialysis]. AU - Szprynger,K, AU - Szczepańska,M, AU - Mazur,B, AU - Dyduch,A, AU - Zwolińska,D, AU - Morawiec-Knysak,A, AU - Makulska,I, PY - 2000/11/9/pubmed PY - 2001/2/28/medline PY - 2000/11/9/entrez SP - 459 EP - 61 JF - Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego JO - Pol. Merkur. Lekarski VL - 8 IS - 49 N2 - In various pathological conditions elevated serum sialic acid level, as the result of increased metabolism of glycoproteins and glycolipids, is observed. The study aimed at the evaluation of sialic acid concentration in serum of children on continuous ambulatory peritoneal dialysis (CAPD) and maintenance haemodialysis (HD). Examination was performed in 27 end-stage renal disease (ESRD) children including 11 on CAPD, 16 on HD treatment. Ten healthy children served as the control group (K). In CAPD group assessment was carried out during the routine monthly check up, in HD group--before (HD-1) and after (HD-2) dialysis session. Sialic acid concentration was determined using method of Shamberger. In CAPD children we obtained significantly increased serum sialic acid concentration comparing to controls and HD children. Increased serum sialic acid concentration was also found in HD children comparing to controls. There was no significant difference between the sialic acid concentrations before and after dialysis session. Analysis of correlation revealed positive correlation of sialic acid concentration with haemoglobin concentration and hematocrit in CAPD group. In children on HD treatment we showed positive correlation of sialic acid level with renal replacement therapy duration and creatinine concentration after HD. Elevated serum sialic acid concentration in dialysed children could be the result of non-specific organism response, characterised by tissue and organ damage, towards the materials of extracorporeal circulation (HD) or the presence of dialysis solution in peritoneal cavity (CAPD). SN - 1426-9686 UR - https://www.unboundmedicine.com/medline/citation/11070713/[Evaluation_of_serum_sialic_acid_concentration_in_chronic_renal_failure_children_on_continuous_ambulatory_peritoneal_dialysis_and_hemodialysis]_ L2 - https://medlineplus.gov/kidneyfailure.html DB - PRIME DP - Unbound Medicine ER -