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Successful eradication of Ascaris lumbricoides and hookworm infection after three repeated doses of albendazole.
J Med Assoc Thai. 2000 Sep; 83(9):1095-100.JM

Abstract

Three repeated orally doses of albendazole 400 mg in 6 weekly intervals were evaluated in Thai hill-tribe students who had at least one kind of soil-transmitted helminths (i.e. Ascaris lumbricoides, hookworm and Trichuris trichiura). Stool examination and parasite egg count were performed using Beaver's standard direct smear method and Kato-Katz's cellophane thick smear method prior to treatment and then 1 month after the first, second and third dose of drug administrations. A single dose of albendazole was very effective against A. lumbricoides and hookworm infections, with cure rates of 98.68 per cent and 92.16 per cent, respectively. The second and third dosages eradicated A. lumbricoides and hookworm infections, respectively. Conversely, the first to third cure rates for T. trichiura infection were relatively low, being 37.76-58.16 per cent. Three repeated doses of albendazole proved to be beneficial in eradication of A. lumbricoides and hookworm infections, and decreased the prevalence of T. trichiura infected cases. For eradication of T. trichiura infection, further regimen and period of drug administration is required.

Authors+Show Affiliations

Department of Parasitology, Chiang Mai University, Thailand.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11075978

Citation

Sukontason, K, et al. "Successful Eradication of Ascaris Lumbricoides and Hookworm Infection After Three Repeated Doses of Albendazole." Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 83, no. 9, 2000, pp. 1095-100.
Sukontason K, Sukontason K, Piangjai S, et al. Successful eradication of Ascaris lumbricoides and hookworm infection after three repeated doses of albendazole. J Med Assoc Thai. 2000;83(9):1095-100.
Sukontason, K., Sukontason, K., Piangjai, S., Na-Bangchang, K., & Karbwang, J. (2000). Successful eradication of Ascaris lumbricoides and hookworm infection after three repeated doses of albendazole. Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, 83(9), 1095-100.
Sukontason K, et al. Successful Eradication of Ascaris Lumbricoides and Hookworm Infection After Three Repeated Doses of Albendazole. J Med Assoc Thai. 2000;83(9):1095-100. PubMed PMID: 11075978.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Successful eradication of Ascaris lumbricoides and hookworm infection after three repeated doses of albendazole. AU - Sukontason,K, AU - Sukontason,K, AU - Piangjai,S, AU - Na-Bangchang,K, AU - Karbwang,J, PY - 2000/11/15/pubmed PY - 2001/2/28/medline PY - 2000/11/15/entrez SP - 1095 EP - 100 JF - Journal of the Medical Association of Thailand = Chotmaihet thangphaet JO - J Med Assoc Thai VL - 83 IS - 9 N2 - Three repeated orally doses of albendazole 400 mg in 6 weekly intervals were evaluated in Thai hill-tribe students who had at least one kind of soil-transmitted helminths (i.e. Ascaris lumbricoides, hookworm and Trichuris trichiura). Stool examination and parasite egg count were performed using Beaver's standard direct smear method and Kato-Katz's cellophane thick smear method prior to treatment and then 1 month after the first, second and third dose of drug administrations. A single dose of albendazole was very effective against A. lumbricoides and hookworm infections, with cure rates of 98.68 per cent and 92.16 per cent, respectively. The second and third dosages eradicated A. lumbricoides and hookworm infections, respectively. Conversely, the first to third cure rates for T. trichiura infection were relatively low, being 37.76-58.16 per cent. Three repeated doses of albendazole proved to be beneficial in eradication of A. lumbricoides and hookworm infections, and decreased the prevalence of T. trichiura infected cases. For eradication of T. trichiura infection, further regimen and period of drug administration is required. SN - 0125-2208 UR - https://www.unboundmedicine.com/medline/citation/11075978/Successful_eradication_of_Ascaris_lumbricoides_and_hookworm_infection_after_three_repeated_doses_of_albendazole_ DB - PRIME DP - Unbound Medicine ER -