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Vulvar hypertrophy with lymphedema. A mimicker of aggressive angiomyxoma.
Arch Pathol Lab Med. 2000 Nov; 124(11):1697-9.AP

Abstract

We report the case of a 43-year-old quadriplegic woman with bilateral vulvar enlargement. The clinical impression was labial hypertrophy, but the microscopic features mimicked aggressive angiomyxoma because of the location, hypocellular proliferation of fibroblastic cells in an edematous-myxoid stroma, and vessels with perivascular collagen deposition, which simulated the thick-walled vessels of aggressive angiomyxoma. Since the lesion lacked true thick-walled vessels and contained ectatic tortuous lymphatics, the pathologic interpretation was lymphedema. This vulvar lesion should be recognized to prevent the misdiagnosis of aggressive angiomyxoma.

Authors+Show Affiliations

Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, TX, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11079029

Citation

Vang, R, et al. "Vulvar Hypertrophy With Lymphedema. a Mimicker of Aggressive Angiomyxoma." Archives of Pathology & Laboratory Medicine, vol. 124, no. 11, 2000, pp. 1697-9.
Vang R, Connelly JH, Hammill HA, et al. Vulvar hypertrophy with lymphedema. A mimicker of aggressive angiomyxoma. Arch Pathol Lab Med. 2000;124(11):1697-9.
Vang, R., Connelly, J. H., Hammill, H. A., & Shannon, R. L. (2000). Vulvar hypertrophy with lymphedema. A mimicker of aggressive angiomyxoma. Archives of Pathology & Laboratory Medicine, 124(11), 1697-9.
Vang R, et al. Vulvar Hypertrophy With Lymphedema. a Mimicker of Aggressive Angiomyxoma. Arch Pathol Lab Med. 2000;124(11):1697-9. PubMed PMID: 11079029.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vulvar hypertrophy with lymphedema. A mimicker of aggressive angiomyxoma. AU - Vang,R, AU - Connelly,J H, AU - Hammill,H A, AU - Shannon,R L, PY - 2000/11/18/pubmed PY - 2001/2/28/medline PY - 2000/11/18/entrez SP - 1697 EP - 9 JF - Archives of pathology & laboratory medicine JO - Arch. Pathol. Lab. Med. VL - 124 IS - 11 N2 - We report the case of a 43-year-old quadriplegic woman with bilateral vulvar enlargement. The clinical impression was labial hypertrophy, but the microscopic features mimicked aggressive angiomyxoma because of the location, hypocellular proliferation of fibroblastic cells in an edematous-myxoid stroma, and vessels with perivascular collagen deposition, which simulated the thick-walled vessels of aggressive angiomyxoma. Since the lesion lacked true thick-walled vessels and contained ectatic tortuous lymphatics, the pathologic interpretation was lymphedema. This vulvar lesion should be recognized to prevent the misdiagnosis of aggressive angiomyxoma. SN - 0003-9985 UR - https://www.unboundmedicine.com/medline/citation/11079029/Vulvar_hypertrophy_with_lymphedema__A_mimicker_of_aggressive_angiomyxoma_ L2 - http://www.archivesofpathology.org/doi/10.1043/0003-9985(2000)124<1697:VHWL>2.0.CO;2?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -