Short wavelength light-induced retinal damage in rats.Jpn J Ophthalmol 2000 Nov-Dec; 44(6):615-9JJ
To evaluate short wavelength light-induced retinal damage in rats.
Pigmented rats were exposed to 300-500 nm wavelength light for 30 seconds, 1, 3, 10, 20, 60, or 90 minutes. Electroretinogram a-, b-, and c-waves were recorded 48 hours after the exposure.
While the a- and b-wave amplitudes were reduced significantly after exposures of 60 minutes and longer, the c-wave amplitude was reduced after only 3 minutes of exposure.
Rat retinal pigment epithelium is more sensitive to damage by exposure to 300-500 nm wavelength light than the neural retina.