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The long-acting Ocusert-pilocarpine system in the management of glaucoma.
Invest Ophthalmol 1975; 14(1):43-6IO

Abstract

The Ocusert-pilocarpine devides with seven days' therapeutic duration were compared with pilocarpine eye drops for efficacy and ocular tolerance in the management of glaucoma in 16 patients. Magnitude of pressure reduction with release rates of 20 mcg. and 40 mcg. of pilocarpine per hour were as effective in the treatment of glaucoma as 2 per cent and 4 per cent pilocarpine eye drops, respectively. Ocular tolerance and retention in the human eyes were good. There were no appreciable side effects other than the occasional sudden leakage phenomenon encountered. Further refinement of the Ocusert-pilocarpine device to reduce the incidence of leakage would not only ensure precision in the rate of drug release, but would also expand its clinical application.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

1110136

Citation

Lee, P, et al. "The Long-acting Ocusert-pilocarpine System in the Management of Glaucoma." Investigative Ophthalmology, vol. 14, no. 1, 1975, pp. 43-6.
Lee P, Shen Y, Eberle M. The long-acting Ocusert-pilocarpine system in the management of glaucoma. Invest Ophthalmol. 1975;14(1):43-6.
Lee, P., Shen, Y., & Eberle, M. (1975). The long-acting Ocusert-pilocarpine system in the management of glaucoma. Investigative Ophthalmology, 14(1), pp. 43-6.
Lee P, Shen Y, Eberle M. The Long-acting Ocusert-pilocarpine System in the Management of Glaucoma. Invest Ophthalmol. 1975;14(1):43-6. PubMed PMID: 1110136.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The long-acting Ocusert-pilocarpine system in the management of glaucoma. AU - Lee,P, AU - Shen,Y, AU - Eberle,M, PY - 1975/1/1/pubmed PY - 1975/1/1/medline PY - 1975/1/1/entrez SP - 43 EP - 6 JF - Investigative ophthalmology JO - Invest Ophthalmol VL - 14 IS - 1 N2 - The Ocusert-pilocarpine devides with seven days' therapeutic duration were compared with pilocarpine eye drops for efficacy and ocular tolerance in the management of glaucoma in 16 patients. Magnitude of pressure reduction with release rates of 20 mcg. and 40 mcg. of pilocarpine per hour were as effective in the treatment of glaucoma as 2 per cent and 4 per cent pilocarpine eye drops, respectively. Ocular tolerance and retention in the human eyes were good. There were no appreciable side effects other than the occasional sudden leakage phenomenon encountered. Further refinement of the Ocusert-pilocarpine device to reduce the incidence of leakage would not only ensure precision in the rate of drug release, but would also expand its clinical application. SN - 0020-9988 UR - https://www.unboundmedicine.com/medline/citation/1110136/The_long_acting_Ocusert_pilocarpine_system_in_the_management_of_glaucoma_ L2 - http://www.diseaseinfosearch.org/result/3065 DB - PRIME DP - Unbound Medicine ER -