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Supradiaphragmatic ectopic adrenocorticotropic hormone-secreting adenoma.
Pathol Int. 2000 Nov; 50(11):901-4.PI

Abstract

A 22-year-old woman with Cushing's syndrome, caused by an extremely rare suprasellar ectopic pituitary adenoma, is presented. Magnetic resonance imaging and computed tomography revealed a well-circumscribed mass in the right suprasellar region. Endocrinological tests showed elevated s-adrenocorticotropic hormone level and hypercortisolemia. The tumor was totally removed by right subfrontal approach. At the time of the operation, the tumor was in continuity with the distal pituitary stalk but not with the pituitary gland. The diaphragma sellae was intact. Histologic diagnosis of the tumor specimen was confirmed as a pituitary adenoma. After surgical removal of the tumor, continued improvement in the patient's laboratory results and disappearance of her endocrine symptoms strongly indicated the absence of adenoma cells in the pituitary gland or stalk. Six years post-surgery, there was no evidence of recurrence in the patient's clinical and laboratory examination. This tumor probably originated from aberrant anterior pituitary cells of the pituitary stalk.

Authors+Show Affiliations

Departments of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam University Hospital and Medical School, Kwangju, Republic of Korea. sjung@chonnam.chonnam.ac.krNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11107067

Citation

Jung, S, et al. "Supradiaphragmatic Ectopic Adrenocorticotropic Hormone-secreting Adenoma." Pathology International, vol. 50, no. 11, 2000, pp. 901-4.
Jung S, Kim JH, Kim TS, et al. Supradiaphragmatic ectopic adrenocorticotropic hormone-secreting adenoma. Pathol Int. 2000;50(11):901-4.
Jung, S., Kim, J. H., Kim, T. S., Lee, M. C., Seo, J. J., Park, J. W., & Kang, S. S. (2000). Supradiaphragmatic ectopic adrenocorticotropic hormone-secreting adenoma. Pathology International, 50(11), 901-4.
Jung S, et al. Supradiaphragmatic Ectopic Adrenocorticotropic Hormone-secreting Adenoma. Pathol Int. 2000;50(11):901-4. PubMed PMID: 11107067.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Supradiaphragmatic ectopic adrenocorticotropic hormone-secreting adenoma. AU - Jung,S, AU - Kim,J H, AU - Kim,T S, AU - Lee,M C, AU - Seo,J J, AU - Park,J W, AU - Kang,S S, PY - 2000/12/7/pubmed PY - 2001/2/28/medline PY - 2000/12/7/entrez SP - 901 EP - 4 JF - Pathology international JO - Pathol Int VL - 50 IS - 11 N2 - A 22-year-old woman with Cushing's syndrome, caused by an extremely rare suprasellar ectopic pituitary adenoma, is presented. Magnetic resonance imaging and computed tomography revealed a well-circumscribed mass in the right suprasellar region. Endocrinological tests showed elevated s-adrenocorticotropic hormone level and hypercortisolemia. The tumor was totally removed by right subfrontal approach. At the time of the operation, the tumor was in continuity with the distal pituitary stalk but not with the pituitary gland. The diaphragma sellae was intact. Histologic diagnosis of the tumor specimen was confirmed as a pituitary adenoma. After surgical removal of the tumor, continued improvement in the patient's laboratory results and disappearance of her endocrine symptoms strongly indicated the absence of adenoma cells in the pituitary gland or stalk. Six years post-surgery, there was no evidence of recurrence in the patient's clinical and laboratory examination. This tumor probably originated from aberrant anterior pituitary cells of the pituitary stalk. SN - 1320-5463 UR - https://www.unboundmedicine.com/medline/citation/11107067/Supradiaphragmatic_ectopic_adrenocorticotropic_hormone_secreting_adenoma_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1320-5463&date=2000&volume=50&issue=11&spage=901 DB - PRIME DP - Unbound Medicine ER -