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Vitamin B12 deficiency and incontinence in older people.
Can J Urol. 2000 Aug; 7(4):1077-80.CJ

Abstract

OBJECTIVES

To investigate the relationship between urinary incontinence and Vitamin B12 deficiency in community-living older people using standard serum cobalamin levels as well as the metabolites methylmalonic acid (MMA) and total homocysteine (HCYS).

DESIGN

A prospective cross-sectional study of community-living older people.

PARTICIPANTS

Independent and cognitively normal adults (mean age=72 years, range=65-89 years) living in the community. One hundred and nineteen volunteers were recruited at group meetings, activity groups, and through the use of posters.

MEASUREMENTS

Information on urinary continence was provided by the participant during a systematic medical history, and was defined as any amount of uncontrolled leakage of urine. Vitamin B12, methylmalonic acid and homocysteine levels were determined in all subjects.

MAIN RESULTS

We found no significant differences between the continent and incontinent group in regard to their serum Vitamin B12 (OR=1.34, CI: 0.39-4.58, p=.424), methylmalonic acid levels (OR=0.71, CI: 0.24-2.10, p=.386), or total homocysteine levels (CI: 0.29-4.54, p=.535).

CONCLUSIONS

In our study continence was not significantly affected by the B12 status of the subject; neither serum B12 levels or the metabolites MMA and HCYS (reflecting B12 function) were significantly different in the continent group versus the incontinent one.

Authors+Show Affiliations

Garcia A
Division Geriatric Medicine, Queen's University, St. Mary's of the Lake Hospital, Kingston, Ontario, Canada.
Smith M
No affiliation info available
Freedman M
No affiliation info available

MeSH

AgedAged, 80 and overCross-Sectional StudiesFemaleHomocysteineHumansMaleMethylmalonic AcidPrevalenceProspective StudiesUrinary IncontinenceVitamin B 12 Deficiency

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11109078

Citation

Garcia, A, et al. "Vitamin B12 Deficiency and Incontinence in Older People." The Canadian Journal of Urology, vol. 7, no. 4, 2000, pp. 1077-80.
Garcia A, Smith M, Freedman M. Vitamin B12 deficiency and incontinence in older people. Can J Urol. 2000;7(4):1077-80.
Garcia, A., Smith, M., & Freedman, M. (2000). Vitamin B12 deficiency and incontinence in older people. The Canadian Journal of Urology, 7(4), 1077-80.
Garcia A, Smith M, Freedman M. Vitamin B12 Deficiency and Incontinence in Older People. Can J Urol. 2000;7(4):1077-80. PubMed PMID: 11109078.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vitamin B12 deficiency and incontinence in older people. AU - Garcia,A, AU - Smith,M, AU - Freedman,M, PY - 2000/12/8/pubmed PY - 2001/6/8/medline PY - 2000/12/8/entrez SP - 1077 EP - 80 JF - The Canadian journal of urology JO - Can J Urol VL - 7 IS - 4 N2 - OBJECTIVES: To investigate the relationship between urinary incontinence and Vitamin B12 deficiency in community-living older people using standard serum cobalamin levels as well as the metabolites methylmalonic acid (MMA) and total homocysteine (HCYS). DESIGN: A prospective cross-sectional study of community-living older people. PARTICIPANTS: Independent and cognitively normal adults (mean age=72 years, range=65-89 years) living in the community. One hundred and nineteen volunteers were recruited at group meetings, activity groups, and through the use of posters. MEASUREMENTS: Information on urinary continence was provided by the participant during a systematic medical history, and was defined as any amount of uncontrolled leakage of urine. Vitamin B12, methylmalonic acid and homocysteine levels were determined in all subjects. MAIN RESULTS: We found no significant differences between the continent and incontinent group in regard to their serum Vitamin B12 (OR=1.34, CI: 0.39-4.58, p=.424), methylmalonic acid levels (OR=0.71, CI: 0.24-2.10, p=.386), or total homocysteine levels (CI: 0.29-4.54, p=.535). CONCLUSIONS: In our study continence was not significantly affected by the B12 status of the subject; neither serum B12 levels or the metabolites MMA and HCYS (reflecting B12 function) were significantly different in the continent group versus the incontinent one. SN - 1195-9479 UR - https://www.unboundmedicine.com/medline/citation/11109078/Vitamin_B12_deficiency_and_incontinence_in_older_people_ L2 - https://www.diseaseinfosearch.org/result/3797 DB - PRIME DP - Unbound Medicine ER -