Tags

Type your tag names separated by a space and hit enter

US of mammographically detected clustered microcalcifications.
Radiology. 2000 Dec; 217(3):849-54.R

Abstract

PURPOSE

To determine whether ultrasonography (US) can depict breast masses associated with mammographically detected clustered microcalcifications and whether the visibility at US is different between benign and malignant lesions.

MATERIALS AND METHODS

Ninety-four patients with 100 mammographically detected microcalcification clusters prospectively underwent US with a 10- or 12-MHz transducer before mammographically guided presurgical hook-wire localization. The visibility of breast masses at US was correlated with histologic and mammographic findings.

RESULTS

Surgical biopsy revealed 62 benign lesions, 30 intraductal cancers, and eight invasive cancers. At US, breast masses associated with microcalcifications were seen in 45 (45%) of 100 cases. US depicted more breast masses associated with malignant (31 [82%] of 38) than with benign (14 [23%] of 62) microcalcifications (P: <.001). In malignant microcalcification clusters larger than 10 mm, US depicted associated breast masses in all 25 cases. There was no statistically significant difference in shape and distribution of calcific particles, as well as in breast composition, at mammography between US visible and invisible groups.

CONCLUSION

Given a known mammographic location, US with a high-frequency transducer can depict breast masses associated with malignant microcalcifications, particularly clusters larger than 10 mm. US can be used to visualize large clusters of microcalcifications that have a very high suspicion of malignancy.

Authors+Show Affiliations

Departments of Radiology, Clinical Research Institute, Seoul National University Hospital and the Institute of Radiation Medicine, SNUMRC, 28 Yongon-Dong, Chongno-Gu, Seoul, Korea. moonwk@radcom.snu.ac.krNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11110953

Citation

Moon, W K., et al. "US of Mammographically Detected Clustered Microcalcifications." Radiology, vol. 217, no. 3, 2000, pp. 849-54.
Moon WK, Im JG, Koh YH, et al. US of mammographically detected clustered microcalcifications. Radiology. 2000;217(3):849-54.
Moon, W. K., Im, J. G., Koh, Y. H., Noh, D. Y., & Park, I. A. (2000). US of mammographically detected clustered microcalcifications. Radiology, 217(3), 849-54.
Moon WK, et al. US of Mammographically Detected Clustered Microcalcifications. Radiology. 2000;217(3):849-54. PubMed PMID: 11110953.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - US of mammographically detected clustered microcalcifications. AU - Moon,W K, AU - Im,J G, AU - Koh,Y H, AU - Noh,D Y, AU - Park,I A, PY - 2000/12/9/pubmed PY - 2001/2/28/medline PY - 2000/12/9/entrez SP - 849 EP - 54 JF - Radiology JO - Radiology VL - 217 IS - 3 N2 - PURPOSE: To determine whether ultrasonography (US) can depict breast masses associated with mammographically detected clustered microcalcifications and whether the visibility at US is different between benign and malignant lesions. MATERIALS AND METHODS: Ninety-four patients with 100 mammographically detected microcalcification clusters prospectively underwent US with a 10- or 12-MHz transducer before mammographically guided presurgical hook-wire localization. The visibility of breast masses at US was correlated with histologic and mammographic findings. RESULTS: Surgical biopsy revealed 62 benign lesions, 30 intraductal cancers, and eight invasive cancers. At US, breast masses associated with microcalcifications were seen in 45 (45%) of 100 cases. US depicted more breast masses associated with malignant (31 [82%] of 38) than with benign (14 [23%] of 62) microcalcifications (P: <.001). In malignant microcalcification clusters larger than 10 mm, US depicted associated breast masses in all 25 cases. There was no statistically significant difference in shape and distribution of calcific particles, as well as in breast composition, at mammography between US visible and invisible groups. CONCLUSION: Given a known mammographic location, US with a high-frequency transducer can depict breast masses associated with malignant microcalcifications, particularly clusters larger than 10 mm. US can be used to visualize large clusters of microcalcifications that have a very high suspicion of malignancy. SN - 0033-8419 UR - https://www.unboundmedicine.com/medline/citation/11110953/US_of_mammographically_detected_clustered_microcalcifications_ L2 - https://pubs.rsna.org/doi/10.1148/radiology.217.3.r00nv27849?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -