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Iron overload in the erythropoietin era.
Nephrol Nurs J. 2000 Apr; 27(2):227-31.NN

Abstract

Increasing use of maintenance parenteral iron in the erythropoietin (EPO) era has been accompanied by growing concern about iron overload. This article attempts to put the issue of iron overload in hemodialysis patients into perspective. The condition is less common in all dialysis patients today than it was in the pre-EPO era, since fewer patients are being transfused and EPO therapy shifts iron into erythroid cells. Patients with end stage renal disease (ESRD) are less likely than patients with hemochromatosis to develop iron-induced organ dysfunction. Diagnosis of iron overload is best accomplished through liver biopsy. Clinically significant iron overload, which rarely occurs if ESRD patients are properly managed, can be treated in most EPO-treated renal failure patients by simply withholding parenteral iron therapy.

Authors+Show Affiliations

Dialysis Services, Hartford Hospital, CT, USA.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

11111550

Citation

Robbins, K C.. "Iron Overload in the Erythropoietin Era." Nephrology Nursing Journal : Journal of the American Nephrology Nurses' Association, vol. 27, no. 2, 2000, pp. 227-31.
Robbins KC. Iron overload in the erythropoietin era. Nephrol Nurs J. 2000;27(2):227-31.
Robbins, K. C. (2000). Iron overload in the erythropoietin era. Nephrology Nursing Journal : Journal of the American Nephrology Nurses' Association, 27(2), 227-31.
Robbins KC. Iron Overload in the Erythropoietin Era. Nephrol Nurs J. 2000;27(2):227-31. PubMed PMID: 11111550.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Iron overload in the erythropoietin era. A1 - Robbins,K C, PY - 2000/12/9/pubmed PY - 2006/6/9/medline PY - 2000/12/9/entrez SP - 227 EP - 31 JF - Nephrology nursing journal : journal of the American Nephrology Nurses' Association JO - Nephrol Nurs J VL - 27 IS - 2 N2 - Increasing use of maintenance parenteral iron in the erythropoietin (EPO) era has been accompanied by growing concern about iron overload. This article attempts to put the issue of iron overload in hemodialysis patients into perspective. The condition is less common in all dialysis patients today than it was in the pre-EPO era, since fewer patients are being transfused and EPO therapy shifts iron into erythroid cells. Patients with end stage renal disease (ESRD) are less likely than patients with hemochromatosis to develop iron-induced organ dysfunction. Diagnosis of iron overload is best accomplished through liver biopsy. Clinically significant iron overload, which rarely occurs if ESRD patients are properly managed, can be treated in most EPO-treated renal failure patients by simply withholding parenteral iron therapy. SN - 1526-744X UR - https://www.unboundmedicine.com/medline/citation/11111550/Iron_overload_in_the_erythropoietin_era_ L2 - https://www.diseaseinfosearch.org/result/3874 DB - PRIME DP - Unbound Medicine ER -