Tags

Type your tag names separated by a space and hit enter

Hypomagnesemia is linked to low serum HDL-cholesterol irrespective of serum glucose values.
J Diabetes Complications 2000 Sep-Oct; 14(5):272-6JD

Abstract

Hypomagnesemia is common in diabetic subjects, and is especially common in poorly controlled diabetes, suggesting that diabetes low serum magnesium status is osmotic diuresis-dependent. To assess the relationship between serum magnesium and HDL-cholesterol concentration adjusted by serum glucose values. We assessed the serum magnesium levels of 50 controlled (HbA(1c)</=7.5% and FPG<126 mg/dl), 110 non-controlled (HbA(1c)>7.5% and FPG>/=126 mg/dl) type II diabetic patients, 40 subjects with impaired fasting glucose (IFG) (FPG>/=110 mg/dl and <126 mg/dl) and 190 healthy volunteers (FPG<110 mg/dl). Healthy volunteers were required to have normal blood pressure and normal laboratory tests. Subjects in the groups included were matched by age and body mass index (BMI). The average of diabetes duration was of 11.4+/-6.6, and 10.9+/-6.2 years, P=NS, for the controlled and non-controlled diabetic patients, respectively. Thirty (60.0%) controlled diabetic subjects, 58 (52. 7%) non-controlled diabetic patients, 21 (52.5%) subjects with IFG, and 39 (20.5%) healthy volunteers had serum magnesium levels </=1.7 mg/l. Serum HDL-cholesterol value showed significant graded increase with serum magnesium levels irrespective of glucose values. Results of this study suggest that hypomagnesemia by an etiopathogenic pathway glycemia independent seems to be involved to decrease HDL-cholesterol.

Authors+Show Affiliations

Medical Research Unit in Clinical Epidemiology, Durango, Mexico. guerrero@omanet.com.mx

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

11113690

Citation

Guerrero-Romero, F, and M Rodríguez-Morán. "Hypomagnesemia Is Linked to Low Serum HDL-cholesterol Irrespective of Serum Glucose Values." Journal of Diabetes and Its Complications, vol. 14, no. 5, 2000, pp. 272-6.
Guerrero-Romero F, Rodríguez-Morán M. Hypomagnesemia is linked to low serum HDL-cholesterol irrespective of serum glucose values. J Diabetes Complicat. 2000;14(5):272-6.
Guerrero-Romero, F., & Rodríguez-Morán, M. (2000). Hypomagnesemia is linked to low serum HDL-cholesterol irrespective of serum glucose values. Journal of Diabetes and Its Complications, 14(5), pp. 272-6.
Guerrero-Romero F, Rodríguez-Morán M. Hypomagnesemia Is Linked to Low Serum HDL-cholesterol Irrespective of Serum Glucose Values. J Diabetes Complicat. 2000;14(5):272-6. PubMed PMID: 11113690.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hypomagnesemia is linked to low serum HDL-cholesterol irrespective of serum glucose values. AU - Guerrero-Romero,F, AU - Rodríguez-Morán,M, PY - 2000/12/13/pubmed PY - 2001/2/28/medline PY - 2000/12/13/entrez SP - 272 EP - 6 JF - Journal of diabetes and its complications JO - J. Diabetes Complicat. VL - 14 IS - 5 N2 - Hypomagnesemia is common in diabetic subjects, and is especially common in poorly controlled diabetes, suggesting that diabetes low serum magnesium status is osmotic diuresis-dependent. To assess the relationship between serum magnesium and HDL-cholesterol concentration adjusted by serum glucose values. We assessed the serum magnesium levels of 50 controlled (HbA(1c)</=7.5% and FPG<126 mg/dl), 110 non-controlled (HbA(1c)>7.5% and FPG>/=126 mg/dl) type II diabetic patients, 40 subjects with impaired fasting glucose (IFG) (FPG>/=110 mg/dl and <126 mg/dl) and 190 healthy volunteers (FPG<110 mg/dl). Healthy volunteers were required to have normal blood pressure and normal laboratory tests. Subjects in the groups included were matched by age and body mass index (BMI). The average of diabetes duration was of 11.4+/-6.6, and 10.9+/-6.2 years, P=NS, for the controlled and non-controlled diabetic patients, respectively. Thirty (60.0%) controlled diabetic subjects, 58 (52. 7%) non-controlled diabetic patients, 21 (52.5%) subjects with IFG, and 39 (20.5%) healthy volunteers had serum magnesium levels </=1.7 mg/l. Serum HDL-cholesterol value showed significant graded increase with serum magnesium levels irrespective of glucose values. Results of this study suggest that hypomagnesemia by an etiopathogenic pathway glycemia independent seems to be involved to decrease HDL-cholesterol. SN - 1056-8727 UR - https://www.unboundmedicine.com/medline/citation/11113690/Hypomagnesemia_is_linked_to_low_serum_HDL_cholesterol_irrespective_of_serum_glucose_values_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1056-8727(00)00127-6 DB - PRIME DP - Unbound Medicine ER -