TY - JOUR T1 - Gas chromatography/ion trap tandem mass spectrometry for the analysis of halobenzenes in soils by solid-phase microextraction. AU - Sarrión,M N, AU - Santos,F J, AU - Galceran,M T, PY - 2000/12/13/pubmed PY - 2001/4/3/medline PY - 2000/12/13/entrez SP - 2271 EP - 81 JF - Rapid communications in mass spectrometry : RCM JO - Rapid Commun Mass Spectrom VL - 14 IS - 23 N2 - Headspace solid-phase microextraction combined with gas chromatography/ion trap tandem mass spectrometry (HS-SPME/GC/ITMS/MS) was used for the analysis of 12 halobenzenes from soil samples. For MS/MS optimisation, the experiments were performed by precursor ion selection and software controlled operations. Collision-induced dissociation (CID) can be achieved by two different approaches, resonant and non-resonant excitation modes. Different results were obtained using the two approaches, and the resonant excitation mode was chosen as the best for all halobenzenes. Parameters such as the CID excitation amplitude, excitation RF storage level and CID bandwidth frequency were optimised to maximise the formation of halobenzene product ions. A 100-microm polydimethylsiloxane fibre was used for the isolation and preconcentration of the analytes. The HS-SPME/GC/ITMS/MS method was applied to the analysis of halobenzenes in an agricultural soil sample. The halobenzenes were quantified by standard addition, which led to good reproducibility (RSD between 4.7 and 9.2%) and detection limits in the low pg/g range. The method was validated by comparing the results with those obtained in a European inter-laboratory exercise. SN - 0951-4198 UR - https://www.unboundmedicine.com/medline/citation/11114038/Gas_chromatography/ion_trap_tandem_mass_spectrometry_for_the_analysis_of_halobenzenes_in_soils_by_solid_phase_microextraction_ DB - PRIME DP - Unbound Medicine ER -