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Atrophoderma of moulin with preceding inflammation.

Abstract

A 16-year-old Vietnamese man presented to the Dermatology Clinic with a 10-year history of bizarre brown patches, which initially started as red asymptomatic "bumps" on the trunk, upper and lower extremities, and face. His past medical history was significant for hypothyroidism and idiopathic urticaria. He was on Eltroxin for hypothyroidism. The family history was noncontributory. Physical examination revealed two types of lesion: erythematous, well-circumscribed papules in a linear configuration along with linear hyperpigmented atrophic patches following Blaschko's lines were noted on the lower extremities (Fig. 1), right upper extremity, right flank (Fig. 2), and right jawline. Initial biopsies taken from the papular lesions on the right thigh and right elbow revealed the following changes. The first biopsy showed a slightly thinned epidermis with prominent dilated blood vessels in the superficial dermis. There also appeared to be a slight increase in the amount of collagen in the deep dermis. The findings were reported as in keeping with "epithelial atrophy." The second biopsy from the lesion on the right elbow revealed an acanthotic epidermis. The granular layer was absent in several areas and there was marked overlying parakeratosis. In the dermis, there was a heavy perivascular lymphocytic infiltrate. The appearances were consistent with a psoriasiform dermatitis (Fig. 3). A biopsy taken from the left thigh approximately 18 months later showed slight irregular acanthosis with dermal edema, dilated blood vessels, and a patchy lymphocytic infiltrate. The appearances were compatible with mild inflammation.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Division of Dermatology, The Wellesley Hospital, and The University of Toronto Medical School, Toronto, Canada.

    Source

    International journal of dermatology 39:11 2000 Nov pg 850-2

    MeSH

    Adolescent
    Atrophy
    Diagnosis, Differential
    Humans
    Hyperpigmentation
    Inflammation
    Male
    Skin

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    11123448

    Citation

    Browne, C, and B K. Fisher. "Atrophoderma of Moulin With Preceding Inflammation." International Journal of Dermatology, vol. 39, no. 11, 2000, pp. 850-2.
    Browne C, Fisher BK. Atrophoderma of moulin with preceding inflammation. Int J Dermatol. 2000;39(11):850-2.
    Browne, C., & Fisher, B. K. (2000). Atrophoderma of moulin with preceding inflammation. International Journal of Dermatology, 39(11), pp. 850-2.
    Browne C, Fisher BK. Atrophoderma of Moulin With Preceding Inflammation. Int J Dermatol. 2000;39(11):850-2. PubMed PMID: 11123448.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Atrophoderma of moulin with preceding inflammation. AU - Browne,C, AU - Fisher,B K, PY - 2000/12/21/pubmed PY - 2001/2/28/medline PY - 2000/12/21/entrez SP - 850 EP - 2 JF - International journal of dermatology JO - Int. J. Dermatol. VL - 39 IS - 11 N2 - A 16-year-old Vietnamese man presented to the Dermatology Clinic with a 10-year history of bizarre brown patches, which initially started as red asymptomatic "bumps" on the trunk, upper and lower extremities, and face. His past medical history was significant for hypothyroidism and idiopathic urticaria. He was on Eltroxin for hypothyroidism. The family history was noncontributory. Physical examination revealed two types of lesion: erythematous, well-circumscribed papules in a linear configuration along with linear hyperpigmented atrophic patches following Blaschko's lines were noted on the lower extremities (Fig. 1), right upper extremity, right flank (Fig. 2), and right jawline. Initial biopsies taken from the papular lesions on the right thigh and right elbow revealed the following changes. The first biopsy showed a slightly thinned epidermis with prominent dilated blood vessels in the superficial dermis. There also appeared to be a slight increase in the amount of collagen in the deep dermis. The findings were reported as in keeping with "epithelial atrophy." The second biopsy from the lesion on the right elbow revealed an acanthotic epidermis. The granular layer was absent in several areas and there was marked overlying parakeratosis. In the dermis, there was a heavy perivascular lymphocytic infiltrate. The appearances were consistent with a psoriasiform dermatitis (Fig. 3). A biopsy taken from the left thigh approximately 18 months later showed slight irregular acanthosis with dermal edema, dilated blood vessels, and a patchy lymphocytic infiltrate. The appearances were compatible with mild inflammation. SN - 0011-9059 UR - https://www.unboundmedicine.com/medline/citation/11123448/Atrophoderma_of_moulin_with_preceding_inflammation_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0011-9059&date=2000&volume=39&issue=11&spage=850 DB - PRIME DP - Unbound Medicine ER -