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Recent advances in phototherapy.
Eur J Dermatol. 2000 Dec; 10(8):642-5.EJ

Abstract

This synopsis reviews recent developments in dermatological phototherapy. UVA1 phototherapy (340-400 nm) is effective in the treatment of inflammatory skin diseases such as acutely exacerbated atopic dermatitis, localized scleroderma, urticaria pigmentosa and disseminated granuloma annulare. Narrowband UVB radiation (311-313 nm) is used successfully as monotherapy or combined with dithranol, oral retinoids or 8-MOP in psoriasis, atopic dermatitis (AD) or photosensitivity disorders such as polymorphic light eruption. Bath water delivery of 8-methoxypsoralen and subsequent UVA-irradiation (PUVA bath therapy) for the treatment of psoriasis as well as for mycosis fungoides, localized scleroderma, urticaria pigmentosa or lichen planus is an effective alternative to its systemic application. The combination of salt water brine baths in different concentrations and subsequent UVA/B irradiation is used increasingly for the treatment of psoriasis or AD. Extracorporeal photopheresis (ECP) has proven to be a very effective treatment modality for cutaneous T cell lymphoma, chronic graft-versus-host disease and certain autoimmune diseases such as systemic scleroderma or pemphigus. However, despite the documented benefits of these new treatment modalities, little data exist as of yet on potential long-term side effects, thus the indications for these therapies should be considered carefully and patients should be followed up at regular intervals.

Authors+Show Affiliations

Department of Dermatology, University of Freiburg, Hauptstr. 7, 79104 Freiburg, Germany. simonj@haut.ukl.uni-freiburg.deNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

11125334

Citation

Simon, J C., et al. "Recent Advances in Phototherapy." European Journal of Dermatology : EJD, vol. 10, no. 8, 2000, pp. 642-5.
Simon JC, Pfieger D, Schöpf E. Recent advances in phototherapy. Eur J Dermatol. 2000;10(8):642-5.
Simon, J. C., Pfieger, D., & Schöpf, E. (2000). Recent advances in phototherapy. European Journal of Dermatology : EJD, 10(8), 642-5.
Simon JC, Pfieger D, Schöpf E. Recent Advances in Phototherapy. Eur J Dermatol. 2000;10(8):642-5. PubMed PMID: 11125334.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Recent advances in phototherapy. AU - Simon,J C, AU - Pfieger,D, AU - Schöpf,E, PY - 2000/12/23/pubmed PY - 2001/2/28/medline PY - 2000/12/23/entrez SP - 642 EP - 5 JF - European journal of dermatology : EJD JO - Eur J Dermatol VL - 10 IS - 8 N2 - This synopsis reviews recent developments in dermatological phototherapy. UVA1 phototherapy (340-400 nm) is effective in the treatment of inflammatory skin diseases such as acutely exacerbated atopic dermatitis, localized scleroderma, urticaria pigmentosa and disseminated granuloma annulare. Narrowband UVB radiation (311-313 nm) is used successfully as monotherapy or combined with dithranol, oral retinoids or 8-MOP in psoriasis, atopic dermatitis (AD) or photosensitivity disorders such as polymorphic light eruption. Bath water delivery of 8-methoxypsoralen and subsequent UVA-irradiation (PUVA bath therapy) for the treatment of psoriasis as well as for mycosis fungoides, localized scleroderma, urticaria pigmentosa or lichen planus is an effective alternative to its systemic application. The combination of salt water brine baths in different concentrations and subsequent UVA/B irradiation is used increasingly for the treatment of psoriasis or AD. Extracorporeal photopheresis (ECP) has proven to be a very effective treatment modality for cutaneous T cell lymphoma, chronic graft-versus-host disease and certain autoimmune diseases such as systemic scleroderma or pemphigus. However, despite the documented benefits of these new treatment modalities, little data exist as of yet on potential long-term side effects, thus the indications for these therapies should be considered carefully and patients should be followed up at regular intervals. SN - 1167-1122 UR - https://www.unboundmedicine.com/medline/citation/11125334/Recent_advances_in_phototherapy_ L2 - https://medlineplus.gov/skinconditions.html DB - PRIME DP - Unbound Medicine ER -