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Mezerein: antileukemic principle isolated from Daphne mezereum L.
Science. 1975 Feb 21; 187(4177):652-3.Sci

Abstract

An alcohol-water extract of Daphne mezereum L., a plant widely used in folk medicine for treating cancers, showed antileukemic activity against the P-388 lymphocytic leukemia in mice. Systematic fractionation of the extract has led to isolation and characterization of mezerein as the principal antileukemic component.

Links

Publisher Full Text

Authors

Kupchan SM
No affiliation info available
Baxter RL
No affiliation info available

MeSH

AnimalsAntineoplastic AgentsLeukemia, ExperimentalLeukemia, LymphoidMicePlant ExtractsPlants, Medicinal

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

1114315

Citation

Kupchan, S M., and R L. Baxter. "Mezerein: Antileukemic Principle Isolated From Daphne Mezereum L." Science (New York, N.Y.), vol. 187, no. 4177, 1975, pp. 652-3.
Kupchan SM, Baxter RL. Mezerein: antileukemic principle isolated from Daphne mezereum L. Science. 1975;187(4177):652-3.
Kupchan, S. M., & Baxter, R. L. (1975). Mezerein: antileukemic principle isolated from Daphne mezereum L. Science (New York, N.Y.), 187(4177), 652-3.
Kupchan SM, Baxter RL. Mezerein: Antileukemic Principle Isolated From Daphne Mezereum L. Science. 1975 Feb 21;187(4177):652-3. PubMed PMID: 1114315.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mezerein: antileukemic principle isolated from Daphne mezereum L. AU - Kupchan,S M, AU - Baxter,R L, PY - 1975/2/21/pubmed PY - 1975/2/21/medline PY - 1975/2/21/entrez SP - 652 EP - 3 JF - Science (New York, N.Y.) JO - Science VL - 187 IS - 4177 N2 - An alcohol-water extract of Daphne mezereum L., a plant widely used in folk medicine for treating cancers, showed antileukemic activity against the P-388 lymphocytic leukemia in mice. Systematic fractionation of the extract has led to isolation and characterization of mezerein as the principal antileukemic component. SN - 0036-8075 UR - https://www.unboundmedicine.com/medline/citation/1114315/Mezerein:_antileukemic_principle_isolated_from_Daphne_mezereum_L_ L2 - https://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=1114315 DB - PRIME DP - Unbound Medicine ER -