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Extragonadal germ cell tumors: clinicopathologic findings, staging and treatment experience in 14 patients.
J Exp Clin Cancer Res. 2000 Sep; 19(3):281-5.JE

Abstract

Extragonadal germ cell tumors (EGCT) are a rare group of neoplasms histologically identical to testicular counterparts. Fourteen cases of primary mediastinal and retroperitoneal germ cell tumors were treated with chemotherapy and radiotherapy between 1987 and 1999 in Ankara Oncology Hospital. There were 9 (64%) complete remissions (CR),one (7%) partial remission (PR) and 2 (14%) stable diseases (SD). The remaining 2 patients were lost due to dissemination of disease. The median duration of response was 19 months. Our modified chemotherapeutic results were similar to original doses of PVB and BEP but toxicity was less. The neccesity of a uniform staging system and treatment programs are discussed.

Authors+Show Affiliations

Dept. of Urologic Oncology and Radiotherapy, Ankara Oncology Education and Research Hospital, Turkey. defne@mail.koc.netNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11144519

Citation

Berkmen, F, et al. "Extragonadal Germ Cell Tumors: Clinicopathologic Findings, Staging and Treatment Experience in 14 Patients." Journal of Experimental & Clinical Cancer Research : CR, vol. 19, no. 3, 2000, pp. 281-5.
Berkmen F, Peker AF, Ayyildiz A, et al. Extragonadal germ cell tumors: clinicopathologic findings, staging and treatment experience in 14 patients. J Exp Clin Cancer Res. 2000;19(3):281-5.
Berkmen, F., Peker, A. F., Ayyildiz, A., Başay, S., Arik, A. I., & Uğur, I. (2000). Extragonadal germ cell tumors: clinicopathologic findings, staging and treatment experience in 14 patients. Journal of Experimental & Clinical Cancer Research : CR, 19(3), 281-5.
Berkmen F, et al. Extragonadal Germ Cell Tumors: Clinicopathologic Findings, Staging and Treatment Experience in 14 Patients. J Exp Clin Cancer Res. 2000;19(3):281-5. PubMed PMID: 11144519.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Extragonadal germ cell tumors: clinicopathologic findings, staging and treatment experience in 14 patients. AU - Berkmen,F, AU - Peker,A F, AU - Ayyildiz,A, AU - Başay,S, AU - Arik,A I, AU - Uğur,I, PY - 2001/1/6/pubmed PY - 2001/3/3/medline PY - 2001/1/6/entrez SP - 281 EP - 5 JF - Journal of experimental & clinical cancer research : CR JO - J. Exp. Clin. Cancer Res. VL - 19 IS - 3 N2 - Extragonadal germ cell tumors (EGCT) are a rare group of neoplasms histologically identical to testicular counterparts. Fourteen cases of primary mediastinal and retroperitoneal germ cell tumors were treated with chemotherapy and radiotherapy between 1987 and 1999 in Ankara Oncology Hospital. There were 9 (64%) complete remissions (CR),one (7%) partial remission (PR) and 2 (14%) stable diseases (SD). The remaining 2 patients were lost due to dissemination of disease. The median duration of response was 19 months. Our modified chemotherapeutic results were similar to original doses of PVB and BEP but toxicity was less. The neccesity of a uniform staging system and treatment programs are discussed. SN - 0392-9078 UR - https://www.unboundmedicine.com/medline/citation/11144519/Extragonadal_germ_cell_tumors:_clinicopathologic_findings_staging_and_treatment_experience_in_14_patients_ DB - PRIME DP - Unbound Medicine ER -