Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children.
In a randomized, double-blind controlled trial, 42 children with irritable bowel syndrome (IBS) were given pH-dependent, enteric-coated peppermint oil capsules or placebo. After 2 weeks, 75% of those receiving peppermint oil had reduced severity of pain associated with IBS. Peppermint oil may be used as a therapeutic agent during the symptomatic phase of IBS.
University of Missouri-Columbia, Department of Child Health, Division of Pediatric Gastroenterology, Columbia, Missouri, USA., ,
Colonic Diseases, Functional
Severity of Illness Index
Pub Type(s)Clinical Trial
Randomized Controlled Trial
Research Support, Non-U.S. Gov't