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Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children.

Abstract

In a randomized, double-blind controlled trial, 42 children with irritable bowel syndrome (IBS) were given pH-dependent, enteric-coated peppermint oil capsules or placebo. After 2 weeks, 75% of those receiving peppermint oil had reduced severity of pain associated with IBS. Peppermint oil may be used as a therapeutic agent during the symptomatic phase of IBS.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    University of Missouri-Columbia, Department of Child Health, Division of Pediatric Gastroenterology, Columbia, Missouri, USA.

    , ,

    Source

    The Journal of pediatrics 138:1 2001 Jan pg 125-8

    MeSH

    Abdominal Pain
    Adolescent
    Age Factors
    Child
    Colonic Diseases, Functional
    Double-Blind Method
    Female
    Humans
    Hydrogen-Ion Concentration
    Male
    Pain Measurement
    Parasympatholytics
    Plant Oils
    Severity of Illness Index
    Tablets, Enteric-Coated
    Treatment Outcome

    Pub Type(s)

    Clinical Trial
    Journal Article
    Multicenter Study
    Randomized Controlled Trial
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    11148527

    Citation

    Kline, R M., et al. "Enteric-coated, pH-dependent Peppermint Oil Capsules for the Treatment of Irritable Bowel Syndrome in Children." The Journal of Pediatrics, vol. 138, no. 1, 2001, pp. 125-8.
    Kline RM, Kline JJ, Di Palma J , et al. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr. 2001;138(1):125-8.
    Kline, R. M., Kline, J. J., Di Palma J, ., & Barbero, G. J. (2001). Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. The Journal of Pediatrics, 138(1), pp. 125-8.
    Kline RM, et al. Enteric-coated, pH-dependent Peppermint Oil Capsules for the Treatment of Irritable Bowel Syndrome in Children. J Pediatr. 2001;138(1):125-8. PubMed PMID: 11148527.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. AU - Kline,R M, AU - Kline,J J, AU - Di Palma J,, AU - Barbero,G J, PY - 2001/1/10/pubmed PY - 2001/3/10/medline PY - 2001/1/10/entrez SP - 125 EP - 8 JF - The Journal of pediatrics JO - J. Pediatr. VL - 138 IS - 1 N2 - In a randomized, double-blind controlled trial, 42 children with irritable bowel syndrome (IBS) were given pH-dependent, enteric-coated peppermint oil capsules or placebo. After 2 weeks, 75% of those receiving peppermint oil had reduced severity of pain associated with IBS. Peppermint oil may be used as a therapeutic agent during the symptomatic phase of IBS. SN - 0022-3476 UR - https://www.unboundmedicine.com/medline/citation/11148527/Enteric_coated_pH_dependent_peppermint_oil_capsules_for_the_treatment_of_irritable_bowel_syndrome_in_children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022347601950693 DB - PRIME DP - Unbound Medicine ER -