Tags

Type your tag names separated by a space and hit enter

Reduction in fat intake is not associated with weight loss in most women after breast cancer diagnosis: evidence from a randomized controlled trial.
Cancer. 2001 Jan 01; 91(1):25-34.C

Abstract

BACKGROUND

A reduction in dietary fat intake has been suggested as a method to promote weight loss in women at risk for breast cancer recurrence.

METHODS

Weight change in response to diet intervention was examined in 1010 women who had completed treatment for Stage I, Stage II, or Stage IIIA (American Joint Committee on Cancer staging system) primary operable breast cancer during their first year of participation in a randomized, controlled, diet intervention trial to reduce risk of recurrence. Diet intervention was performed by telephone counseling and promoted a low fat diet that also was high in fiber, vegetables, and fruit. The comparison group was provided with general dietary guidelines to reduce disease risk. Multiple linear regression models were used to examine the relations among demographic and personal characteristics, changes in diet composition and exercise level, and change in body weight or body mass index.

RESULTS

The average weight change in the 1-year period was 0.04 kg for the intervention group and 0.46 kg for the comparison group. For the total group, body weight was stable (+/- 5% baseline weight) for 743 women (74%), whereas 114 (11%) lost weight, and 153 (15%) gained weight. These distributions were similar in the two study groups inclusive of all study participants and for only those women with a baseline body mass index of > or = 25 kg/m2. Initial body mass index and changes in fiber and vegetable intakes, but not change in percent of energy obtained from fat, were associated independently with change in weight or body mass index.

CONCLUSIONS

For most women at risk for breast cancer recurrence, diet intervention to promote a reduction in fat intake was not associated with significant weight loss. Testing the effect of a substantial change in diet composition on risk for breast cancer recurrence is unlikely to be confounded by weight loss in subjects who were the recipients of intensive intervention efforts.

Authors+Show Affiliations

Rock CL
Department of Family and Preventive Medicine and Cancer Prevention and Control Program, University of California at San Diego, La Jolla, California 92093-0901, USA. clrock@ucsd.edu
Thomson C
No affiliation info available
Caan BJ
No affiliation info available
Flatt SW
No affiliation info available
Newman V
No affiliation info available
Ritenbaugh C
No affiliation info available
Marshall JR
No affiliation info available
Hollenbach KA
No affiliation info available
Stefanick ML
No affiliation info available
Pierce JP
No affiliation info available

MeSH

AdultAgedBody Mass IndexBreast NeoplasmsDiet, ReducingDietary FatsDietary FiberExerciseFemaleFruitHumansMiddle AgedNeoplasm Recurrence, LocalObesityRisk FactorsVegetablesWeight Loss

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

11148556

Citation

Rock, C L., et al. "Reduction in Fat Intake Is Not Associated With Weight Loss in Most Women After Breast Cancer Diagnosis: Evidence From a Randomized Controlled Trial." Cancer, vol. 91, no. 1, 2001, pp. 25-34.
Rock CL, Thomson C, Caan BJ, et al. Reduction in fat intake is not associated with weight loss in most women after breast cancer diagnosis: evidence from a randomized controlled trial. Cancer. 2001;91(1):25-34.
Rock, C. L., Thomson, C., Caan, B. J., Flatt, S. W., Newman, V., Ritenbaugh, C., Marshall, J. R., Hollenbach, K. A., Stefanick, M. L., & Pierce, J. P. (2001). Reduction in fat intake is not associated with weight loss in most women after breast cancer diagnosis: evidence from a randomized controlled trial. Cancer, 91(1), 25-34.
Rock CL, et al. Reduction in Fat Intake Is Not Associated With Weight Loss in Most Women After Breast Cancer Diagnosis: Evidence From a Randomized Controlled Trial. Cancer. 2001 Jan 1;91(1):25-34. PubMed PMID: 11148556.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reduction in fat intake is not associated with weight loss in most women after breast cancer diagnosis: evidence from a randomized controlled trial. AU - Rock,C L, AU - Thomson,C, AU - Caan,B J, AU - Flatt,S W, AU - Newman,V, AU - Ritenbaugh,C, AU - Marshall,J R, AU - Hollenbach,K A, AU - Stefanick,M L, AU - Pierce,J P, PY - 2001/1/10/pubmed PY - 2002/1/5/medline PY - 2001/1/10/entrez SP - 25 EP - 34 JF - Cancer JO - Cancer VL - 91 IS - 1 N2 - BACKGROUND: A reduction in dietary fat intake has been suggested as a method to promote weight loss in women at risk for breast cancer recurrence. METHODS: Weight change in response to diet intervention was examined in 1010 women who had completed treatment for Stage I, Stage II, or Stage IIIA (American Joint Committee on Cancer staging system) primary operable breast cancer during their first year of participation in a randomized, controlled, diet intervention trial to reduce risk of recurrence. Diet intervention was performed by telephone counseling and promoted a low fat diet that also was high in fiber, vegetables, and fruit. The comparison group was provided with general dietary guidelines to reduce disease risk. Multiple linear regression models were used to examine the relations among demographic and personal characteristics, changes in diet composition and exercise level, and change in body weight or body mass index. RESULTS: The average weight change in the 1-year period was 0.04 kg for the intervention group and 0.46 kg for the comparison group. For the total group, body weight was stable (+/- 5% baseline weight) for 743 women (74%), whereas 114 (11%) lost weight, and 153 (15%) gained weight. These distributions were similar in the two study groups inclusive of all study participants and for only those women with a baseline body mass index of > or = 25 kg/m2. Initial body mass index and changes in fiber and vegetable intakes, but not change in percent of energy obtained from fat, were associated independently with change in weight or body mass index. CONCLUSIONS: For most women at risk for breast cancer recurrence, diet intervention to promote a reduction in fat intake was not associated with significant weight loss. Testing the effect of a substantial change in diet composition on risk for breast cancer recurrence is unlikely to be confounded by weight loss in subjects who were the recipients of intensive intervention efforts. SN - 0008-543X UR - https://www.unboundmedicine.com/medline/citation/11148556/Reduction_in_fat_intake_is_not_associated_with_weight_loss_in_most_women_after_breast_cancer_diagnosis:_evidence_from_a_randomized_controlled_trial_ DB - PRIME DP - Unbound Medicine ER -