Tags

Type your tag names separated by a space and hit enter

Second-derivative spectrophotometric assay of pseudoephedrine, ibuprofen and loratadine in pharmaceuticals.
Arzneimittelforschung. 2000 Nov; 50(11):1004-8.A

Abstract

In this paper the second-derivative spectrophotometric method for the simultaneous determination of pseudoephedrine (CAS 90-82-4) in the combinations with ibuprofen (CAS 15687-27-1) and loratadine (CAS 79794-75-5) is described. Optimal conditions for the quantitative analysis of coated tablets (Test I) and tablets (Test II) were settled. The second-derivative order of the spectra in ethanol with the wavelength modulation was used. For the quantitative assay for all of the investigated substances in the laboratory mixture or in respective pharmaceutical dosage forms the "zero-crossing" technique was applied. The authors propose this second-derivative spectrophotometry for a rapid, simple, precise and accurate determination of the mentioned tests or a corresponding multicomponent mixture.

Authors+Show Affiliations

Ivanovic D
Institute of Pharmaceutical Chemistry and Drug Analysis, Belgrade, Yugoslavia.
Medenica M
No affiliation info available
Markovic S
No affiliation info available
Mandic G
No affiliation info available

MeSH

Anti-Allergic AgentsAnti-Inflammatory Agents, Non-SteroidalCalibrationDrug CombinationsEphedrineIbuprofenLoratadineNasal DecongestantsSpectrophotometry, UltravioletTablets, Enteric-Coated

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11148855

Citation

Ivanovic, D, et al. "Second-derivative Spectrophotometric Assay of Pseudoephedrine, Ibuprofen and Loratadine in Pharmaceuticals." Arzneimittel-Forschung, vol. 50, no. 11, 2000, pp. 1004-8.
Ivanovic D, Medenica M, Markovic S, et al. Second-derivative spectrophotometric assay of pseudoephedrine, ibuprofen and loratadine in pharmaceuticals. Arzneimittelforschung. 2000;50(11):1004-8.
Ivanovic, D., Medenica, M., Markovic, S., & Mandic, G. (2000). Second-derivative spectrophotometric assay of pseudoephedrine, ibuprofen and loratadine in pharmaceuticals. Arzneimittel-Forschung, 50(11), 1004-8.
Ivanovic D, et al. Second-derivative Spectrophotometric Assay of Pseudoephedrine, Ibuprofen and Loratadine in Pharmaceuticals. Arzneimittelforschung. 2000;50(11):1004-8. PubMed PMID: 11148855.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Second-derivative spectrophotometric assay of pseudoephedrine, ibuprofen and loratadine in pharmaceuticals. AU - Ivanovic,D, AU - Medenica,M, AU - Markovic,S, AU - Mandic,G, PY - 2001/1/10/pubmed PY - 2001/3/3/medline PY - 2001/1/10/entrez SP - 1004 EP - 8 JF - Arzneimittel-Forschung JO - Arzneimittelforschung VL - 50 IS - 11 N2 - In this paper the second-derivative spectrophotometric method for the simultaneous determination of pseudoephedrine (CAS 90-82-4) in the combinations with ibuprofen (CAS 15687-27-1) and loratadine (CAS 79794-75-5) is described. Optimal conditions for the quantitative analysis of coated tablets (Test I) and tablets (Test II) were settled. The second-derivative order of the spectra in ethanol with the wavelength modulation was used. For the quantitative assay for all of the investigated substances in the laboratory mixture or in respective pharmaceutical dosage forms the "zero-crossing" technique was applied. The authors propose this second-derivative spectrophotometry for a rapid, simple, precise and accurate determination of the mentioned tests or a corresponding multicomponent mixture. SN - 0004-4172 UR - https://www.unboundmedicine.com/medline/citation/11148855/Second_derivative_spectrophotometric_assay_of_pseudoephedrine_ibuprofen_and_loratadine_in_pharmaceuticals_ DB - PRIME DP - Unbound Medicine ER -
Grapherence [↓3]

Related Citations

More