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Differences between features of adenoma in the rectum versus sigmoid colon.
Am J Gastroenterol. 2000 Dec; 95(12):3620-3.AJ

Abstract

OBJECTIVE

Although the prevalence of cancer in the rectosigmoid is high compared with that in the more proximal colon, the features of cancer developing from an adenoma have yet to be elucidated. The aim of this study is to examine the clinicopathological relationship between cancer and adenoma in the rectosigmoid.

METHODS

A total of 340 adenomas located in the rectosigmoid in 255 patients were retrospectively examined regarding such clinicopathological factors as location and the grade of dysplasia.

RESULTS

The prevalence of adenoma was 102 in the rectum and 238 in the sigmoid colon, respectively, whereas the prevalence of adenoma with high-grade dysplasia was 39 in the rectum and 48 in the sigmoid colon, respectively. This prevalence of adenoma with high-grade dysplasia was thus significantly higher in the rectum than in the sigmoid colon (p < 0.02).

CONCLUSIONS

These findings suggest the possibility of different types of cancer development between adenoma of the rectum and sigmoid colon.

Authors+Show Affiliations

Ikeda Y
Department of Surgery and Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan.
Mori M
No affiliation info available
Akagi K
No affiliation info available
Iwashita A
No affiliation info available
Haraguchi Y
No affiliation info available
Maehara Y
No affiliation info available
Sugimachi K
No affiliation info available

MeSH

AdenocarcinomaAdenomaAdenomatous PolypsColon, SigmoidFemaleHumansMaleMiddle AgedPrevalenceRectal NeoplasmsRectumRetrospective StudiesSigmoid Neoplasms

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

11151902

Citation

Ikeda, Y, et al. "Differences Between Features of Adenoma in the Rectum Versus Sigmoid Colon." The American Journal of Gastroenterology, vol. 95, no. 12, 2000, pp. 3620-3.
Ikeda Y, Mori M, Akagi K, et al. Differences between features of adenoma in the rectum versus sigmoid colon. Am J Gastroenterol. 2000;95(12):3620-3.
Ikeda, Y., Mori, M., Akagi, K., Iwashita, A., Haraguchi, Y., Maehara, Y., & Sugimachi, K. (2000). Differences between features of adenoma in the rectum versus sigmoid colon. The American Journal of Gastroenterology, 95(12), 3620-3.
Ikeda Y, et al. Differences Between Features of Adenoma in the Rectum Versus Sigmoid Colon. Am J Gastroenterol. 2000;95(12):3620-3. PubMed PMID: 11151902.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Differences between features of adenoma in the rectum versus sigmoid colon. AU - Ikeda,Y, AU - Mori,M, AU - Akagi,K, AU - Iwashita,A, AU - Haraguchi,Y, AU - Maehara,Y, AU - Sugimachi,K, PY - 2001/1/11/pubmed PY - 2001/2/28/medline PY - 2001/1/11/entrez SP - 3620 EP - 3 JF - The American journal of gastroenterology JO - Am J Gastroenterol VL - 95 IS - 12 N2 - OBJECTIVE: Although the prevalence of cancer in the rectosigmoid is high compared with that in the more proximal colon, the features of cancer developing from an adenoma have yet to be elucidated. The aim of this study is to examine the clinicopathological relationship between cancer and adenoma in the rectosigmoid. METHODS: A total of 340 adenomas located in the rectosigmoid in 255 patients were retrospectively examined regarding such clinicopathological factors as location and the grade of dysplasia. RESULTS: The prevalence of adenoma was 102 in the rectum and 238 in the sigmoid colon, respectively, whereas the prevalence of adenoma with high-grade dysplasia was 39 in the rectum and 48 in the sigmoid colon, respectively. This prevalence of adenoma with high-grade dysplasia was thus significantly higher in the rectum than in the sigmoid colon (p < 0.02). CONCLUSIONS: These findings suggest the possibility of different types of cancer development between adenoma of the rectum and sigmoid colon. SN - 0002-9270 UR - https://www.unboundmedicine.com/medline/citation/11151902/Differences_between_features_of_adenoma_in_the_rectum_versus_sigmoid_colon_ DB - PRIME DP - Unbound Medicine ER -