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Antioxidants in vegan diet and rheumatic disorders.
Toxicology 2000; 155(1-3):45-53T

Abstract

Plants are rich natural sources of antioxidants in addition to other nutrients. Interventions and cross sectional studies on subjects consuming uncooked vegan diet called living food (LF) have been carried out. We have clarified the efficacy of LF in rheumatoid diseases as an example of a health problem where inflammation is one of the main concerns. LF is an uncooked vegan diet and consists of berries, fruits, vegetables and roots, nuts, germinated seeds and sprouts, i.e. rich sources of carotenoids, vitamins C and E. The subjects eating LF showed highly increased levels of beta and alfa carotenes, lycopen and lutein in their sera. Also the increases of vitamin C and vitamin E (adjusted to cholesterol) were statistically significant. As the berry intake was 3-fold compared to controls the intake of polyphenolic compounds like quercetin, myricetin and kaempherol was much higher than in the omnivorous controls. The LF diet is rich in fibre, substrate of lignan production, and the urinary excretion of polyphenols like enterodiol and enterolactone as well as secoisolaricirecinol were much increased in subjects eating LF. The shift of fibromyalgic subjects to LF resulted in a decrease of their joint stiffness and pain as well as an improvement of their self-experienced health. The rheumatoid arthritis patients eating the LF diet also reported similar positive responses and the objective measures supported this finding. The improvement of rheumatoid arthritis was significantly correlated with the day-to-day fluctuation of subjective symptoms. In conclusion the rheumatoid patients subjectively benefited from the vegan diet rich in antioxidants, lactobacilli and fibre, and this was also seen in objective measures.

Authors+Show Affiliations

Department of Physiology, University of Kuopio, Finland. osmo.hanninen@uku.fiNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

11156742

Citation

Hänninen, , et al. "Antioxidants in Vegan Diet and Rheumatic Disorders." Toxicology, vol. 155, no. 1-3, 2000, pp. 45-53.
Hänninen , Kaartinen K, Rauma AL, et al. Antioxidants in vegan diet and rheumatic disorders. Toxicology. 2000;155(1-3):45-53.
Hänninen, ., Kaartinen, K., Rauma, A. L., Nenonen, M., Törrönen, R., Häkkinen, A. S., ... Laakso, J. (2000). Antioxidants in vegan diet and rheumatic disorders. Toxicology, 155(1-3), pp. 45-53.
Hänninen , et al. Antioxidants in Vegan Diet and Rheumatic Disorders. Toxicology. 2000 Nov 30;155(1-3):45-53. PubMed PMID: 11156742.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidants in vegan diet and rheumatic disorders. AU - Hänninen,, AU - Kaartinen,K, AU - Rauma,A L, AU - Nenonen,M, AU - Törrönen,R, AU - Häkkinen,A S, AU - Adlercreutz,H, AU - Laakso,J, PY - 2001/1/13/pubmed PY - 2001/2/28/medline PY - 2001/1/13/entrez SP - 45 EP - 53 JF - Toxicology JO - Toxicology VL - 155 IS - 1-3 N2 - Plants are rich natural sources of antioxidants in addition to other nutrients. Interventions and cross sectional studies on subjects consuming uncooked vegan diet called living food (LF) have been carried out. We have clarified the efficacy of LF in rheumatoid diseases as an example of a health problem where inflammation is one of the main concerns. LF is an uncooked vegan diet and consists of berries, fruits, vegetables and roots, nuts, germinated seeds and sprouts, i.e. rich sources of carotenoids, vitamins C and E. The subjects eating LF showed highly increased levels of beta and alfa carotenes, lycopen and lutein in their sera. Also the increases of vitamin C and vitamin E (adjusted to cholesterol) were statistically significant. As the berry intake was 3-fold compared to controls the intake of polyphenolic compounds like quercetin, myricetin and kaempherol was much higher than in the omnivorous controls. The LF diet is rich in fibre, substrate of lignan production, and the urinary excretion of polyphenols like enterodiol and enterolactone as well as secoisolaricirecinol were much increased in subjects eating LF. The shift of fibromyalgic subjects to LF resulted in a decrease of their joint stiffness and pain as well as an improvement of their self-experienced health. The rheumatoid arthritis patients eating the LF diet also reported similar positive responses and the objective measures supported this finding. The improvement of rheumatoid arthritis was significantly correlated with the day-to-day fluctuation of subjective symptoms. In conclusion the rheumatoid patients subjectively benefited from the vegan diet rich in antioxidants, lactobacilli and fibre, and this was also seen in objective measures. SN - 0300-483X UR - https://www.unboundmedicine.com/medline/citation/11156742/Antioxidants_in_vegan_diet_and_rheumatic_disorders_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0300-483X(00)00276-6 DB - PRIME DP - Unbound Medicine ER -