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Antioxidants in vegan diet and rheumatic disorders.

Abstract

Plants are rich natural sources of antioxidants in addition to other nutrients. Interventions and cross sectional studies on subjects consuming uncooked vegan diet called living food (LF) have been carried out. We have clarified the efficacy of LF in rheumatoid diseases as an example of a health problem where inflammation is one of the main concerns. LF is an uncooked vegan diet and consists of berries, fruits, vegetables and roots, nuts, germinated seeds and sprouts, i.e. rich sources of carotenoids, vitamins C and E. The subjects eating LF showed highly increased levels of beta and alfa carotenes, lycopen and lutein in their sera. Also the increases of vitamin C and vitamin E (adjusted to cholesterol) were statistically significant. As the berry intake was 3-fold compared to controls the intake of polyphenolic compounds like quercetin, myricetin and kaempherol was much higher than in the omnivorous controls. The LF diet is rich in fibre, substrate of lignan production, and the urinary excretion of polyphenols like enterodiol and enterolactone as well as secoisolaricirecinol were much increased in subjects eating LF. The shift of fibromyalgic subjects to LF resulted in a decrease of their joint stiffness and pain as well as an improvement of their self-experienced health. The rheumatoid arthritis patients eating the LF diet also reported similar positive responses and the objective measures supported this finding. The improvement of rheumatoid arthritis was significantly correlated with the day-to-day fluctuation of subjective symptoms. In conclusion the rheumatoid patients subjectively benefited from the vegan diet rich in antioxidants, lactobacilli and fibre, and this was also seen in objective measures.

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  • Authors+Show Affiliations

    ,

    Department of Physiology, University of Kuopio, Finland. osmo.hanninen@uku.fi

    , , , , , ,

    Source

    Toxicology 155:1-3 2000 Nov 30 pg 45-53

    MeSH

    Antioxidants
    Arthritis, Rheumatoid
    Carotenoids
    Chromatography, High Pressure Liquid
    Diet, Vegetarian
    Dietary Fiber
    Eating
    Female
    Fibromyalgia
    Flavonoids
    Flavonols
    Fruit
    Humans
    Lactobacillus
    Lignans
    Middle Aged
    Severity of Illness Index
    Treatment Outcome
    Vegetables

    Pub Type(s)

    Clinical Trial
    Journal Article
    Randomized Controlled Trial

    Language

    eng

    PubMed ID

    11156742

    Citation

    Hänninen, , et al. "Antioxidants in Vegan Diet and Rheumatic Disorders." Toxicology, vol. 155, no. 1-3, 2000, pp. 45-53.
    Hänninen , Kaartinen K, Rauma AL, et al. Antioxidants in vegan diet and rheumatic disorders. Toxicology. 2000;155(1-3):45-53.
    Hänninen, ., Kaartinen, K., Rauma, A. L., Nenonen, M., Törrönen, R., Häkkinen, A. S., ... Laakso, J. (2000). Antioxidants in vegan diet and rheumatic disorders. Toxicology, 155(1-3), pp. 45-53.
    Hänninen , et al. Antioxidants in Vegan Diet and Rheumatic Disorders. Toxicology. 2000 Nov 30;155(1-3):45-53. PubMed PMID: 11156742.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Antioxidants in vegan diet and rheumatic disorders. AU - Hänninen,, AU - Kaartinen,K, AU - Rauma,A L, AU - Nenonen,M, AU - Törrönen,R, AU - Häkkinen,A S, AU - Adlercreutz,H, AU - Laakso,J, PY - 2001/1/13/pubmed PY - 2001/2/28/medline PY - 2001/1/13/entrez SP - 45 EP - 53 JF - Toxicology JO - Toxicology VL - 155 IS - 1-3 N2 - Plants are rich natural sources of antioxidants in addition to other nutrients. Interventions and cross sectional studies on subjects consuming uncooked vegan diet called living food (LF) have been carried out. We have clarified the efficacy of LF in rheumatoid diseases as an example of a health problem where inflammation is one of the main concerns. LF is an uncooked vegan diet and consists of berries, fruits, vegetables and roots, nuts, germinated seeds and sprouts, i.e. rich sources of carotenoids, vitamins C and E. The subjects eating LF showed highly increased levels of beta and alfa carotenes, lycopen and lutein in their sera. Also the increases of vitamin C and vitamin E (adjusted to cholesterol) were statistically significant. As the berry intake was 3-fold compared to controls the intake of polyphenolic compounds like quercetin, myricetin and kaempherol was much higher than in the omnivorous controls. The LF diet is rich in fibre, substrate of lignan production, and the urinary excretion of polyphenols like enterodiol and enterolactone as well as secoisolaricirecinol were much increased in subjects eating LF. The shift of fibromyalgic subjects to LF resulted in a decrease of their joint stiffness and pain as well as an improvement of their self-experienced health. The rheumatoid arthritis patients eating the LF diet also reported similar positive responses and the objective measures supported this finding. The improvement of rheumatoid arthritis was significantly correlated with the day-to-day fluctuation of subjective symptoms. In conclusion the rheumatoid patients subjectively benefited from the vegan diet rich in antioxidants, lactobacilli and fibre, and this was also seen in objective measures. SN - 0300-483X UR - https://www.unboundmedicine.com/medline/citation/11156742/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S0300-483X(00)00276-6 DB - PRIME DP - Unbound Medicine ER -