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CTA in patients with acute subarachnoid haemorrhage. A comparative study with selective, digital angiography and blinded, independent review.
Acta Radiol. 2001 Jan; 42(1):43-9.AR

Abstract

PURPOSE

Minimal- or non-invasive methods replacing intra-arterial digital subtraction angiography (IA-DSA) would be of great importance in patients suffering from acute subarachnoid haemorrhage (SAH). The aims of this study were to compare CTA with IA-DSA in patients with acute SAH, to compare CTA interpretations with those of blinded, independent reviewers and to evaluate improvement in CTA diagnostics after 1 year of experience with CTA.

MATERIAL AND METHOD

During 2 years 162 patients with SAH underwent CTA as well as IA-DSA. Independent blinded review of 77 patients was performed for 1 year.

RESULTS

Totally 144 aneurysms were demonstrated in 119 patients at IA-DSA, while 43 patients had normal intracranial arteries. Initially 131 aneurysms were detected at CTA while 2 normal, tortuous arteries were misinterpreted as aneurysms, giving a sensitivity of 91% and a specificity of 95%. At independent blinded review the observer agreement was 87% and the kappa value 0.68.

CONCLUSION

CTA in SAH is of great value in demonstrating vascular anatomy and the exact size of an aneurysm. However, IA-DSA is still needed for diagnostic evaluation in aneurysms smaller than 5 mm in diameter, especially in those located near bony structures.

Authors+Show Affiliations

Department of Radiology, The National Hospital, University of Oslo, Norway.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article

Language

eng

PubMed ID

11167331

Citation

Pedersen, H K., et al. "CTA in Patients With Acute Subarachnoid Haemorrhage. a Comparative Study With Selective, Digital Angiography and Blinded, Independent Review." Acta Radiologica (Stockholm, Sweden : 1987), vol. 42, no. 1, 2001, pp. 43-9.
Pedersen HK, Bakke SJ, Hald JK, et al. CTA in patients with acute subarachnoid haemorrhage. A comparative study with selective, digital angiography and blinded, independent review. Acta Radiol. 2001;42(1):43-9.
Pedersen, H. K., Bakke, S. J., Hald, J. K., Skalpe, I. O., Anke, I. M., Sagsveen, R., Langmoen, I. A., Lindegaard, K. E., & Nakstad, P. H. (2001). CTA in patients with acute subarachnoid haemorrhage. A comparative study with selective, digital angiography and blinded, independent review. Acta Radiologica (Stockholm, Sweden : 1987), 42(1), 43-9.
Pedersen HK, et al. CTA in Patients With Acute Subarachnoid Haemorrhage. a Comparative Study With Selective, Digital Angiography and Blinded, Independent Review. Acta Radiol. 2001;42(1):43-9. PubMed PMID: 11167331.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - CTA in patients with acute subarachnoid haemorrhage. A comparative study with selective, digital angiography and blinded, independent review. AU - Pedersen,H K, AU - Bakke,S J, AU - Hald,J K, AU - Skalpe,I O, AU - Anke,I M, AU - Sagsveen,R, AU - Langmoen,I A, AU - Lindegaard,K E, AU - Nakstad,P H, PY - 2001/2/13/pubmed PY - 2001/3/14/medline PY - 2001/2/13/entrez SP - 43 EP - 9 JF - Acta radiologica (Stockholm, Sweden : 1987) JO - Acta Radiol VL - 42 IS - 1 N2 - PURPOSE: Minimal- or non-invasive methods replacing intra-arterial digital subtraction angiography (IA-DSA) would be of great importance in patients suffering from acute subarachnoid haemorrhage (SAH). The aims of this study were to compare CTA with IA-DSA in patients with acute SAH, to compare CTA interpretations with those of blinded, independent reviewers and to evaluate improvement in CTA diagnostics after 1 year of experience with CTA. MATERIAL AND METHOD: During 2 years 162 patients with SAH underwent CTA as well as IA-DSA. Independent blinded review of 77 patients was performed for 1 year. RESULTS: Totally 144 aneurysms were demonstrated in 119 patients at IA-DSA, while 43 patients had normal intracranial arteries. Initially 131 aneurysms were detected at CTA while 2 normal, tortuous arteries were misinterpreted as aneurysms, giving a sensitivity of 91% and a specificity of 95%. At independent blinded review the observer agreement was 87% and the kappa value 0.68. CONCLUSION: CTA in SAH is of great value in demonstrating vascular anatomy and the exact size of an aneurysm. However, IA-DSA is still needed for diagnostic evaluation in aneurysms smaller than 5 mm in diameter, especially in those located near bony structures. SN - 0284-1851 UR - https://www.unboundmedicine.com/medline/citation/11167331/CTA_in_patients_with_acute_subarachnoid_haemorrhage__A_comparative_study_with_selective_digital_angiography_and_blinded_independent_review_ DB - PRIME DP - Unbound Medicine ER -