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Prevalence of hepatitis B, hepatitis C, GB virus C/hepatitis G and TT viruses in predialysis and hemodialysis patients.
J Med Virol. 2001 Feb; 63(2):103-7.JM

Abstract

Patients with chronic renal failure on hemodialysis have a high risk of infections with viruses such as hepatitis B (HBV), hepatitis C (HCV), GB virus C/hepatitis G (GBV-C/HGV) and TT (TTV) viruses. The prevalence of HBV, HCV, GBV-C/HGV and TTV in patients with chronic renal failure who are on conservative management before entering into a hemodialysis program (predialysis) in comparison with hemodialyzed patients was studied to elucidate whether the high prevalence of these viruses is influenced by that observed in the predialysis stage. The presence of hepatitis B virus surface antigen (HBsAg), HCV RNA, GBV-C/HGV RNA and TTV DNA was analyzed in sera from 80 patients with chronic renal failure (35 on predialysis and 45 on hemodialysis). HBsAg, HCV RNA, GBV-C/HGV RNA and TTV DNA were detected in one (2.8%), six (17.1%), eight (22.5%) and 16 (45.7%) of the 35 patients on predialysis. Two (5.7%) of these patients were coinfected with HCV and GBV-C/HGV, whereas six (17.1%) had GBV-C/HGV and TTV coinfection. In the 45 hemodialyzed patients, HBsAg, HCV RNA, GBV-C/HGV RNA and TTV DNA were detected in one (2.2%), two (4.4%), seven (15.5%) and 26 (57.7%). One (2.2%) patient had HBV and TTV coinfection, two (4.4%) HCV and TTV coinfection whereas four (8.8%) were coinfected with GBV-C/HGV and TTV. No differences regarding age, gender, previous surgery and number of transfusions were found between infected and uninfected patients within and between both groups. In conclusion, the prevalence of the viruses studied in predialysis may influence their prevalence in dialysis units.

Authors+Show Affiliations

Department of Hepatology, Fundación Jiménez Díaz and Fundación para el Estudio de las Hepatitis Virales, Madrid, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11170045

Citation

López-Alcorocho, J M., et al. "Prevalence of Hepatitis B, Hepatitis C, GB Virus C/hepatitis G and TT Viruses in Predialysis and Hemodialysis Patients." Journal of Medical Virology, vol. 63, no. 2, 2001, pp. 103-7.
López-Alcorocho JM, Barril G, Ortiz-Movilla N, et al. Prevalence of hepatitis B, hepatitis C, GB virus C/hepatitis G and TT viruses in predialysis and hemodialysis patients. J Med Virol. 2001;63(2):103-7.
López-Alcorocho, J. M., Barril, G., Ortiz-Movilla, N., Traver, J. A., Bartolomé, J., Sanz, P., Selgas, R., & Carreño, V. (2001). Prevalence of hepatitis B, hepatitis C, GB virus C/hepatitis G and TT viruses in predialysis and hemodialysis patients. Journal of Medical Virology, 63(2), 103-7.
López-Alcorocho JM, et al. Prevalence of Hepatitis B, Hepatitis C, GB Virus C/hepatitis G and TT Viruses in Predialysis and Hemodialysis Patients. J Med Virol. 2001;63(2):103-7. PubMed PMID: 11170045.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of hepatitis B, hepatitis C, GB virus C/hepatitis G and TT viruses in predialysis and hemodialysis patients. AU - López-Alcorocho,J M, AU - Barril,G, AU - Ortiz-Movilla,N, AU - Traver,J A, AU - Bartolomé,J, AU - Sanz,P, AU - Selgas,R, AU - Carreño,V, PY - 2001/2/15/pubmed PY - 2001/5/1/medline PY - 2001/2/15/entrez SP - 103 EP - 7 JF - Journal of medical virology JO - J. Med. Virol. VL - 63 IS - 2 N2 - Patients with chronic renal failure on hemodialysis have a high risk of infections with viruses such as hepatitis B (HBV), hepatitis C (HCV), GB virus C/hepatitis G (GBV-C/HGV) and TT (TTV) viruses. The prevalence of HBV, HCV, GBV-C/HGV and TTV in patients with chronic renal failure who are on conservative management before entering into a hemodialysis program (predialysis) in comparison with hemodialyzed patients was studied to elucidate whether the high prevalence of these viruses is influenced by that observed in the predialysis stage. The presence of hepatitis B virus surface antigen (HBsAg), HCV RNA, GBV-C/HGV RNA and TTV DNA was analyzed in sera from 80 patients with chronic renal failure (35 on predialysis and 45 on hemodialysis). HBsAg, HCV RNA, GBV-C/HGV RNA and TTV DNA were detected in one (2.8%), six (17.1%), eight (22.5%) and 16 (45.7%) of the 35 patients on predialysis. Two (5.7%) of these patients were coinfected with HCV and GBV-C/HGV, whereas six (17.1%) had GBV-C/HGV and TTV coinfection. In the 45 hemodialyzed patients, HBsAg, HCV RNA, GBV-C/HGV RNA and TTV DNA were detected in one (2.2%), two (4.4%), seven (15.5%) and 26 (57.7%). One (2.2%) patient had HBV and TTV coinfection, two (4.4%) HCV and TTV coinfection whereas four (8.8%) were coinfected with GBV-C/HGV and TTV. No differences regarding age, gender, previous surgery and number of transfusions were found between infected and uninfected patients within and between both groups. In conclusion, the prevalence of the viruses studied in predialysis may influence their prevalence in dialysis units. SN - 0146-6615 UR - https://www.unboundmedicine.com/medline/citation/11170045/Prevalence_of_hepatitis_B_hepatitis_C_GB_virus_C/hepatitis_G_and_TT_viruses_in_predialysis_and_hemodialysis_patients_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0146-6615&date=2001&volume=63&issue=2&spage=103 DB - PRIME DP - Unbound Medicine ER -