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Prevalence and prognostic importance of hypomagnesemia and hypocalcemia in horses that have colic surgery.
Am J Vet Res. 2001 Jan; 62(1):7-12.AJ

Abstract

OBJECTIVE

To determine the prevalence of hypomagnesemia and hypocalcemia in horses with surgical colic.

ANIMALS

35 horses with surgically managed colic.

PROCEDURE

Serum concentrations of total magnesium (tMg2+) and calcium (tCa2+), as well as ionized magnesium (iMg2+) and calcium (iCa2+) were analyzed before surgery and 1, 3, 5, and 7 days following surgery. A lead-II ECG and pertinent clinical data were also obtained at each time.

RESULTS

Preoperative serum tMg2+ and iMg2+ concentrations were below the reference range in 6 (17%) and 19 (54%) horses, respectively. Serum concentrations of tCa2+ and iCa2+ were less than the reference range in 20 (57%) and 30 (86%) horses before surgery. Horses with strangulating lesions of the gastrointestinal tract had significantly lower preoperative serum concentrations of iMg2+ and iCa2+, as well as a higher heart rate than horses with nonstrangulating lesions. Horses that developed postoperative ileus had significantly lower serum concentrations of iMg2+ after surgery. Serum concentrations of magnesium and calcium (total and ionized) correlated significantly with the PR, QRS, QT, and corrected QT (QTc) intervals. Horses that were euthanatized at the time of surgery (n = 7) had significantly lower preoperative serum concentrations of iMg2+, compared with horses that survived. Neither serum magnesium nor calcium concentrations were predictors of hospitalization time or survival.

CONCLUSIONS AND CLINICAL RELEVANCE

Hypomagnesemia and hypocalcemia were common during the perioperative period, particularly in horses with strangulating intestinal lesions and ileus. Serum concentrations of tMg2+ and tCa2+ were less sensitive than iMg2+ and iCa2+ in detecting horses with hypomagnesemia and hypocalcemia.

Authors+Show Affiliations

Department of Clinical Sciences, Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11197564

Citation

Garcia-Lopez, J M., et al. "Prevalence and Prognostic Importance of Hypomagnesemia and Hypocalcemia in Horses That Have Colic Surgery." American Journal of Veterinary Research, vol. 62, no. 1, 2001, pp. 7-12.
Garcia-Lopez JM, Provost PJ, Rush JE, et al. Prevalence and prognostic importance of hypomagnesemia and hypocalcemia in horses that have colic surgery. Am J Vet Res. 2001;62(1):7-12.
Garcia-Lopez, J. M., Provost, P. J., Rush, J. E., Zicker, S. C., Burmaster, H., & Freeman, L. M. (2001). Prevalence and prognostic importance of hypomagnesemia and hypocalcemia in horses that have colic surgery. American Journal of Veterinary Research, 62(1), 7-12.
Garcia-Lopez JM, et al. Prevalence and Prognostic Importance of Hypomagnesemia and Hypocalcemia in Horses That Have Colic Surgery. Am J Vet Res. 2001;62(1):7-12. PubMed PMID: 11197564.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and prognostic importance of hypomagnesemia and hypocalcemia in horses that have colic surgery. AU - Garcia-Lopez,J M, AU - Provost,P J, AU - Rush,J E, AU - Zicker,S C, AU - Burmaster,H, AU - Freeman,L M, PY - 2001/2/24/pubmed PY - 2001/4/3/medline PY - 2001/2/24/entrez SP - 7 EP - 12 JF - American journal of veterinary research JO - Am. J. Vet. Res. VL - 62 IS - 1 N2 - OBJECTIVE: To determine the prevalence of hypomagnesemia and hypocalcemia in horses with surgical colic. ANIMALS: 35 horses with surgically managed colic. PROCEDURE: Serum concentrations of total magnesium (tMg2+) and calcium (tCa2+), as well as ionized magnesium (iMg2+) and calcium (iCa2+) were analyzed before surgery and 1, 3, 5, and 7 days following surgery. A lead-II ECG and pertinent clinical data were also obtained at each time. RESULTS: Preoperative serum tMg2+ and iMg2+ concentrations were below the reference range in 6 (17%) and 19 (54%) horses, respectively. Serum concentrations of tCa2+ and iCa2+ were less than the reference range in 20 (57%) and 30 (86%) horses before surgery. Horses with strangulating lesions of the gastrointestinal tract had significantly lower preoperative serum concentrations of iMg2+ and iCa2+, as well as a higher heart rate than horses with nonstrangulating lesions. Horses that developed postoperative ileus had significantly lower serum concentrations of iMg2+ after surgery. Serum concentrations of magnesium and calcium (total and ionized) correlated significantly with the PR, QRS, QT, and corrected QT (QTc) intervals. Horses that were euthanatized at the time of surgery (n = 7) had significantly lower preoperative serum concentrations of iMg2+, compared with horses that survived. Neither serum magnesium nor calcium concentrations were predictors of hospitalization time or survival. CONCLUSIONS AND CLINICAL RELEVANCE: Hypomagnesemia and hypocalcemia were common during the perioperative period, particularly in horses with strangulating intestinal lesions and ileus. Serum concentrations of tMg2+ and tCa2+ were less sensitive than iMg2+ and iCa2+ in detecting horses with hypomagnesemia and hypocalcemia. SN - 0002-9645 UR - https://www.unboundmedicine.com/medline/citation/11197564/Prevalence_and_prognostic_importance_of_hypomagnesemia_and_hypocalcemia_in_horses_that_have_colic_surgery_ L2 - http://avmajournals.avma.org/doi/full/10.2460/ajvr.2001.62.7?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -