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Estimation of antithyroid antibodies occurrence in children with coeliac disease.
Med Sci Monit 2000 Jul-Aug; 6(4):719-21MS

Abstract

INTRODUCTION

The coexistence of coeliac disease (CD) and the diseases of autoimmune origin is often discussed in literature. In this study the evaluation of antithyroid antibodies (antimicrosomal-TMA, anti-thyreoglobulin-ATG, thyroid peroxidase antibodies anti-TPO) occurrence against clinical and laboratory determinants of thyroid function is demonstrated in children with coeliac disease.

MATERIAL AND METHODS

The study was conducted on 34 IgA-EmA positive children; control group consisted of 28 children with negative screening tests for coeliac disease.

RESULTS

In both groups, the level of antithyroid antibodies (TMA, ATG, anti-TPO) and determinants of thyroid gland function (TSH, fT3, fT4) were evaluated; USG examination of thyroid gland was also performed. Elevated titres of antithyroid antibodies observed in children with coeliac disease (41.1%) in comparison to control group (3.56%) indicate the need for performing the screening tests for antithyroid antibodies in children with CD.

Authors+Show Affiliations

Department of Gastroenterology and Paediatric Allergology, Institute of Paediatrics, Medical University, ul. Spoma 36/50, 91-738 Łódź, Poland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11208398

Citation

Kowalska, E, et al. "Estimation of Antithyroid Antibodies Occurrence in Children With Coeliac Disease." Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, vol. 6, no. 4, 2000, pp. 719-21.
Kowalska E, Wasowska-Królikowska K, Toporowska-Kowalska E. Estimation of antithyroid antibodies occurrence in children with coeliac disease. Med Sci Monit. 2000;6(4):719-21.
Kowalska, E., Wasowska-Królikowska, K., & Toporowska-Kowalska, E. (2000). Estimation of antithyroid antibodies occurrence in children with coeliac disease. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 6(4), pp. 719-21.
Kowalska E, Wasowska-Królikowska K, Toporowska-Kowalska E. Estimation of Antithyroid Antibodies Occurrence in Children With Coeliac Disease. Med Sci Monit. 2000;6(4):719-21. PubMed PMID: 11208398.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Estimation of antithyroid antibodies occurrence in children with coeliac disease. AU - Kowalska,E, AU - Wasowska-Królikowska,K, AU - Toporowska-Kowalska,E, PY - 2001/2/24/pubmed PY - 2001/4/6/medline PY - 2001/2/24/entrez SP - 719 EP - 21 JF - Medical science monitor : international medical journal of experimental and clinical research JO - Med. Sci. Monit. VL - 6 IS - 4 N2 - INTRODUCTION: The coexistence of coeliac disease (CD) and the diseases of autoimmune origin is often discussed in literature. In this study the evaluation of antithyroid antibodies (antimicrosomal-TMA, anti-thyreoglobulin-ATG, thyroid peroxidase antibodies anti-TPO) occurrence against clinical and laboratory determinants of thyroid function is demonstrated in children with coeliac disease. MATERIAL AND METHODS: The study was conducted on 34 IgA-EmA positive children; control group consisted of 28 children with negative screening tests for coeliac disease. RESULTS: In both groups, the level of antithyroid antibodies (TMA, ATG, anti-TPO) and determinants of thyroid gland function (TSH, fT3, fT4) were evaluated; USG examination of thyroid gland was also performed. Elevated titres of antithyroid antibodies observed in children with coeliac disease (41.1%) in comparison to control group (3.56%) indicate the need for performing the screening tests for antithyroid antibodies in children with CD. SN - 1234-1010 UR - https://www.unboundmedicine.com/medline/citation/11208398/Estimation_of_antithyroid_antibodies_occurrence_in_children_with_coeliac_disease_ L2 - https://www.medscimonit.com/download/index/idArt/508186 DB - PRIME DP - Unbound Medicine ER -