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Pseudodementia in a twenty-one-year-old with bipolar disorder and vitamin B12 and folate deficiency.
West Indian Med J. 2000 Dec; 49(4):347-8.WI

Abstract

A twenty-one-year-old female known to suffer from bipolar type I disorder developed features of a pseudodementia. Following prompt initial response to treatment with antidepressants, there was an early recurrence of cognitive impairment. Blood investigations confirmed a macrocytic anaemia and vitamin B12 and folate deficiencies. There was dramatic resolution of cognitive impairment after vitamin replacement. This suggested the occurrence of a reversible nutritional dementia and reinforced the need to rule out secondary organic causes of psychiatric symptoms even in patients previously diagnosed with a primary psychiatric disorder.

Authors+Show Affiliations

Reid SD
Department of Clinical Medical Sciences, Faculty of Medical Sciences, University of the West Indies, St Augustine, Trinidad and Tobago. reid@carib-link.net

MeSH

AdultBipolar DisorderDementiaFemaleFolic AcidFolic Acid DeficiencyHumansVitamin B 12Vitamin B 12 Deficiency

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11211551

Citation

Reid, S D.. "Pseudodementia in a Twenty-one-year-old With Bipolar Disorder and Vitamin B12 and Folate Deficiency." The West Indian Medical Journal, vol. 49, no. 4, 2000, pp. 347-8.
Reid SD. Pseudodementia in a twenty-one-year-old with bipolar disorder and vitamin B12 and folate deficiency. West Indian Med J. 2000;49(4):347-8.
Reid, S. D. (2000). Pseudodementia in a twenty-one-year-old with bipolar disorder and vitamin B12 and folate deficiency. The West Indian Medical Journal, 49(4), 347-8.
Reid SD. Pseudodementia in a Twenty-one-year-old With Bipolar Disorder and Vitamin B12 and Folate Deficiency. West Indian Med J. 2000;49(4):347-8. PubMed PMID: 11211551.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pseudodementia in a twenty-one-year-old with bipolar disorder and vitamin B12 and folate deficiency. A1 - Reid,S D, PY - 2001/2/24/pubmed PY - 2001/5/5/medline PY - 2001/2/24/entrez SP - 347 EP - 8 JF - The West Indian medical journal JO - West Indian Med J VL - 49 IS - 4 N2 - A twenty-one-year-old female known to suffer from bipolar type I disorder developed features of a pseudodementia. Following prompt initial response to treatment with antidepressants, there was an early recurrence of cognitive impairment. Blood investigations confirmed a macrocytic anaemia and vitamin B12 and folate deficiencies. There was dramatic resolution of cognitive impairment after vitamin replacement. This suggested the occurrence of a reversible nutritional dementia and reinforced the need to rule out secondary organic causes of psychiatric symptoms even in patients previously diagnosed with a primary psychiatric disorder. SN - 0043-3144 UR - https://www.unboundmedicine.com/medline/citation/11211551/Pseudodementia_in_a_twenty_one_year_old_with_bipolar_disorder_and_vitamin_B12_and_folate_deficiency_ DB - PRIME DP - Unbound Medicine ER -